Relanab 1000 mg (Tablet)
Unit Price: ৳ 28.00 (2 x 6: ৳ 336.00)
Strip Price: ৳ 168.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Nabumetone |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Relief of signs and symptoms of osteoarthritis
- Relief of signs and symptoms of rheumatoid arthritis
- Consideration of potential benefits and risks before use
- Use of lowest effective dose
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Anti-inflammatory properties
- Analgesic properties
- Antipyretic properties
- Mode of action not fully known
- Inhibition of prostaglandin synthesis
Dosage & Administration
- Dosage options: 500mg, 750mg, 1000mg
- Oral administration
- Recommended starting dose of 1000mg
- Option for single or twice-daily dose
- Special dosage considerations for renal insufficiency
- No established pediatric dosage
Interaction
- Potential interaction with ACE-inhibitors
- Consideration for patients taking NSAIDs with ACE-inhibitors
Contraindications
- Contraindication in patients with known hypersensitivity
- Contraindication in patients with history of asthma
- Contraindication in patients with history of urticaria
- Contraindication in patients with history of allergic-type reactions to aspirin or other NSAIDs
- Contraindication for peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal side effects: diarrhea, dyspepsia, abdominal pain, constipation, flatulence, nausea, vomiting
- Central Nervous System side effects: dizziness, headache, fatigue, increased sweating, insomnia
- Dermatologic side effects: pruritus, rash
- Special Senses side effects: tinnitus
- Miscellaneous: edema
Pregnancy & Lactation
- Pregnancy Category C
- Limited studies in pregnant women
- Use during pregnancy only if clearly needed
- Caution during third trimester
- Not recommended for nursing mothers
Precautions & Warnings
- Association with renal papillary necrosis and abnormal renal pathology
- Potential renal toxicity in patients with reduced renal blood flow or blood volume
- Patients at greatest risk: impaired renal function, heart failure, liver dysfunction, diuretic use, elderly
- Recovery after discontinuation of NSAID therapy
Overdose Effects
- Symptoms of acute NSAIDs overdoses
- Supportive care for overdose management
- No specific antidotes
- Management with emesis, activated charcoal, osmotic cathartic
- Rare occurrences of hypertension, acute renal failure, respiratory depression, coma
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs for Rheumatoid Arthritis
Storage Conditions
- Storage in cool and dry place
- Protection from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular formula: C15H16O2
Common Questions about Relanab 1000 mg Tablet
- Relief of pain and inflammation
- Use with food or milk to prevent upset stomach
- Long-term use caution
- Caution for activities requiring concentration
- Avoidance of alcohol consumption
- Informing doctor about history of heart disease or stroke
- Regular monitoring for long-term treatment