Eporise 2000 IU (IV/SC Injection)

2000 IU pre-filled syringe: ৳ 1,000.00

Medicine Details

Indications

  • Treatment of anemia in Chronic Kidney Disease (CKD) patients on dialysis and not on dialysis
  • Treatment of anemia in Zidovudine-treated HIV-infected patients
  • Treatment of anemia in patients undergoing concomitant myelosuppressive chemotherapy
  • Reduction of allogeneic RBC transfusions in noncardiac, nonvascular surgery patients
  • Prevention of anemia of prematurity in infants with specific birth weight and gestational age

Description

Recombinant human erythropoietin (EPO) expressed in Chinese hamster ovary cells with a 165 amino acid sequence identical to that of human urinary EPO

Dosage

  • Evaluation of Iron Stores and Nutritional Factors before and during treatment
  • Monitoring hemoglobin levels and adjusting therapy for CKD patients
  • Recommended starting dose for CKD patients on dialysis and not on dialysis
  • Dose adjustments for Zidovudine-treated HIV-infected Patients and patients on cancer chemotherapy

Administration

  • Do not shake or use Erythropoietin alfa that has been shaken or frozen
  • Protect syringe from light
  • Visual inspection for particulate matter and discoloration prior to administration

Interaction

Effect may be potentiated by simultaneous therapeutic administration of a haematinic agent

Contraindications

  • Uncontrolled hypertension
  • Serious allergic reactions to Erythropoietin alfa
  • Patients who develop Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin

Side Effects

  • Adverse reactions in CKD patients, Zidovudine-treated HIV-infected Patients, Cancer Patients on Chemotherapy, Surgery Patients, and Premature infants

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Use with caution in nursing women

Overdose Effects

Wide therapeutic margin with potential for causing hemoglobin levels above desired level

Therapeutic Class

Drugs for Haemolytic Hypoplastic & Renal Anemia

Storage Conditions

Store at 2°C to 8°C and protect from light

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