Ticfree 12.5 mg (Tablet)
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tetrabenazine |
| Company | Everest pharmaceuticals ltd |
Indications
- Treatment of chorea associated with Huntington's disease
Pharmacology
- Vesicular monoamine transporter-2 (VMAT-2) inhibitor
Dosage & Administration
- Can be taken with or without food
- Individualization of dose with weekly titration
Recommended Starting Dose
- 12.5 mg daily
Pediatric & geriatric use
- Safety and effectiveness not established
Interaction
- Reduction in dose with strong CYP2D6 inhibitors
- At least 20 days gap after stopping reserpine
- No interaction with food
Contraindications
- Actively suicidal or untreated/undertreated depression
- Hepatic impairment
- Concurrent use of MAOIs, reserpine, deutetrabenazine, or valbenazine
Common Side Effects
- Sedation/somnolence
- Fatigue
- Insomnia
- Depression
- Akathisia
- Anxiety/aggravated anxiety
- Nausea
Rare Side Effects
- Suicidal thoughts
- Neuroleptic malignant syndrome
- Pneumonia
Pregnancy & Lactation
- No adequate data on developmental risk in pregnant women
- No data on presence in human milk
Precautions & Warnings
- Periodic re-evaluation of benefit and potential adverse effects
- Maximum daily dose not to exceed 50 mg/day
- Maximum single dose not to exceed 25 mg with strong CYP2D6 inhibitors
- Discontinue treatment in case of Neuroleptic Malignant Syndrome
- Impairment of ability to drive or operate machinery
- Not recommended in combination with drugs that prolong QTc
Overdose Effects
- Drowsiness
- Sweating
- Hypothermia
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Cool & dry place
- Protected from light & moisture