Ivacard 7.5 mg (Tablet)

Title

• Ivacard Tablet

Categories

• Medicines
• Cardiovascular Drugs
• Anti-Anginal Drugs

Description

• Symptomatic treatment of chronic stable angina pectoris in coronary artery disease patients with normal sinus rhythm.
• Pure heart rate lowering agent
• Selectively and specifically inhibits the cardiac pacemaker I f current
• Decreases heart rate and cardiac workload, reducing oxygen consumption
• Prolongs diastole for increased perfusion of coronary arteries
• Effects specific to the sinus node with no effect on intra-atrial, atrioventricular or intraventricular conduction times, nor on myocardial contractility or ventricular repolarization

Dosage

• Usual recommended starting dose of 5 mg twice daily
• Increased to 7.5 mg twice daily after 3-4 weeks
• Dose adjustment in elderly, renal insufficiency, and hepatic impairment patients
• Not recommended for children and adolescents

Interactions

• Not recommended with QT wave prolonging medicinal products
• Close cardiac monitoring necessary if concomitant use is essential

Contraindications

• Resting heart rate below 60 bpm
• Cardiogenic shock
• Acute myocardial infarction
• Severe hypotension
• Severe hepatic insufficiency
• Sick sinus syndrome
• Sino-atrial block
• Heart failure
• Pacemaker dependent
• Unstable angina
• 3rd degree AV block
• Combination with strong cytochrome P-450 3A4 inhibitors

Side Effects

• Visual symptoms
• Blurred vision
• Bradycardia
• 1st degree AV block
• Ventricular extrasystoles
• Headaches
• Dizziness

Pregnancy & Lactation

• Contraindicated during pregnancy
• Excreted in breast milk, therefore contra-indicated during breastfeeding

Precautions & Warnings

• Mild to moderate hypotension
• Atrial fibrillation
• Congenital QT syndrome or treated with QT wave prolonging medicinal products
• Moderate hepatic insufficiency
• Severe renal insufficiency

Therapeutic Class

• Other Anti-anginal & Anti-ischaemic drugs

Storage Conditions

• Keep below 30°C temperature
• Away from light & moisture
• Keep out of the reach of children

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