Itrazen 200 mg (Tablet)

Unit Price: ৳ 28.00 (2 x 10: ৳ 560.00)
Strip Price: ৳ 280.00

Medicine Details

Category Details
Generic Itraconazole
Company Beacon pharmaceuticals plc
Also available as

Title

Itrazen 200 mg Tablet

Categories

  • Antifungal Medication
  • Therapeutic Drugs

Description

Itrazen 200 mg Tablet is used for the treatment of various fungal infections, and it inhibits Cytochrome P-450 dependent enzymes.

Dosage

  • 100 mg preparation
  • 200 mg preparation
  • 65 mg preparation
  • 130 mg preparation
  • Pediatric use

Indications

  • Oropharyngeal candidiasis
  • Vulvovaginal candidiasis
  • Tinea pedis
  • Tinea cruris
  • Tinea corporis
  • Tinea manuum
  • Onychomycosis
  • Histoplasmosis
  • Systemic candidiasis
  • Aspergillosis
  • Cryptococcosis
  • Maintenance therapy in AIDS patients
  • Prevention of fungal infection during prolonged neutropenia

Mode of Action

  • Inhibits Cytochrome P-450 dependent enzymes
  • Impairs biosynthesis of ergosterol
  • Utilizes SUBA (Super Bio-available) technology
  • Improves the dissolution of poorly soluble drugs

Interaction

  • Terfenadine
  • Astemizole
  • Cisapride
  • HMG-CoA reductase inhibitors such as simvastatin
  • Rifampin
  • Phenytoin
  • Phenobarbital
  • Digoxin
  • Calcium channel blockers

Contraindications

  • Known hypersensitivity to the drug or any ingredient
  • Severe hepatic disease
  • Patients taking rifampin

Side Effects

  • Nausea
  • Abdominal pain
  • Dyspepsia
  • Constipation
  • Headache
  • Dizziness
  • Raised liver enzymes
  • Menstrual disorders
  • Allergic reactions
  • Hepatitis and cholestatic jaundice
  • Peripheral neuropathy
  • Stevens-Johnson syndrome
  • Hypokalaemia
  • Oedema
  • Hair loss

Pregnancy & Lactation

  • Contraindicated in pregnancy
  • Not recommended during breastfeeding

Precautions & Warnings

  • Absorption impaired when gastric acidity is reduced
  • Administered after a full meal
  • Monitor liver function in patients receiving continuous treatment
  • Rare cases of hepatitis and jaundice reported

Therapeutic Class

Drugs for subcutaneous and mycoses

Storage Conditions

Store below 25°C, in a cool & dry place, away from light and out of the reach of children

Commonly Asked Questions

  • Duration of effect
  • Onset of action
  • Pregnancy warnings
  • Habit forming
  • Breastfeeding warnings

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