Gentin 20 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 6.08 (5 x 5: ৳ 152.00)

Medicine Details

Category	Details
Generic	Gentamicin sulfate injection
Company	Opsonin pharma ltd
Also available as	Gentin 80 mg injection

Indications

Treatment of serious infections caused by susceptible strains of microorganisms
Used for treating conditions like septicaemia, meningitis, respiratory tract infections, infected wounds, skin and soft tissue infections, bone infections, urinary tract infections

Pharmacology

Proven bactericidal antibiotic
Active against a broad spectrum of Gram-negative pathogens
Active against some Gram-positive organisms
Interferes with bacterial protein synthesis

Dosage & Administration

Given by intramuscular route
Usual adult dose of 3-5 mg/kg/day in three divided doses
Pediatric dosage based on age
For intravenous administration, Gentamicin should be diluted with sterile normal saline or 5% glucose in water

Interaction

Avoid concurrent use with potentially nephrotoxic or ototoxic drugs
Potent diuretics may potentiate ototoxic effects of Gentamicin
Inactivated by solutions containing beta-lactam antibiotics

Side Effects

Vestibular damage
Reversible nephrotoxicity
Auditory ototoxicity
Adverse renal effects
Symptoms include dizziness, vertigo, tinnitus, hearing loss

Pregnancy & Lactation

Safety for use in pregnancy and lactation not established
Gentamicin crosses the placenta
Risk of ototoxicity in the fetus
Small amounts detected in breast milk

Therapeutic Class

Aminoglycosides

Storage Conditions

Store in cool and dry place

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