Gentin 20 mg/2 ml (IM/IV Injection)
2 ml ampoule: ৳ 6.08 (5 x 5: ৳ 152.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Gentamicin sulfate injection |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of serious infections caused by susceptible strains of microorganisms
- Used for treating conditions like septicaemia, meningitis, respiratory tract infections, infected wounds, skin and soft tissue infections, bone infections, urinary tract infections
Pharmacology
- Proven bactericidal antibiotic
- Active against a broad spectrum of Gram-negative pathogens
- Active against some Gram-positive organisms
- Interferes with bacterial protein synthesis
Dosage & Administration
- Given by intramuscular route
- Usual adult dose of 3-5 mg/kg/day in three divided doses
- Pediatric dosage based on age
- For intravenous administration, Gentamicin should be diluted with sterile normal saline or 5% glucose in water
Interaction
- Avoid concurrent use with potentially nephrotoxic or ototoxic drugs
- Potent diuretics may potentiate ototoxic effects of Gentamicin
- Inactivated by solutions containing beta-lactam antibiotics
Side Effects
- Vestibular damage
- Reversible nephrotoxicity
- Auditory ototoxicity
- Adverse renal effects
- Symptoms include dizziness, vertigo, tinnitus, hearing loss
Pregnancy & Lactation
- Safety for use in pregnancy and lactation not established
- Gentamicin crosses the placenta
- Risk of ototoxicity in the fetus
- Small amounts detected in breast milk
Therapeutic Class
- Aminoglycosides
Storage Conditions
- Store in cool and dry place