Queta XR 300 mg (Tablet (Extended Release))
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of Acute and chronic psychoses
- Schizophrenia
- Bipolar Disorder
- Manic episodes
- Depressive episodes associated with bipolar disorder
- Maintenance treatment of bipolar I disorder
Pharmacology
- Atypical psychotropic agent
- Dibenzothiazepine derivatives
- Antagonist at neurotransmitter receptors
- Unknown mechanism of action
- Mediated through dopamine D2 and serotonin 5HT2 antagonism
Dosage & Administration
- Administered twice daily
- Dosage titration
- Usual effective dose range of 300-450 mg/day
- Maximum dose of 750 mg/day
- Dosage adjustments based on clinical response
Interaction
- Caution with medicines causing electrolyte imbalance
- Caution with medicines increasing QT interval
- Co-administration effects with thioridazine, carbamazepine, and phenytoin
Contraindications
- Hypersensitivity
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Withdrawal symptoms
- Elevations in serum triglyceride levels
- Elevations in total cholesterol
- Decreases in HDL cholesterol
- Weight gain
- Extrapyramidal symptoms
Pregnancy & Lactation
- Use only if benefits justify potential risks
- Lowest possible dose and duration for pregnancy
- Avoid breastfeeding
Precautions & Warnings
- Increased risk of suicidal thoughts
- Caution in patients with cardiovascular disease
- Caution in patients with seizures
- Consideration for tardive dyskinesia and EPS
- Caution in patients with history of QT prolongation
- Risk of neutropenia
- Observation for hyperglycemia and diabetes mellitus
Use in Special Populations
- Caution in the elderly
- Special considerations for dose titration in elderly
- Not indicated for use in children and adolescents below 18 years of age
Overdose Effects
- Reported survival in acute overdoses
- No specific antidote
- Intensive care procedures recommended
- Treatment for refractory hypotension
- Close medical supervision and monitoring
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of the sight and reach of children
- Do not use after expiry date
- Store in a cool and dry place away from light