Disogen 0.5 mg (Tablet)
Unit Price: ৳ 6.00 (10 x 10: ৳ 600.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Biogen pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome
- Adjunct in the treatment of seizures
- Long-term use not systematically studied
Pharmacology
- Exhibits anticonvulsive, sedative, muscle relaxing and anxiolytic effects
- Mediates actions through enhancement of GABAergic neurotransmission
Dosage & Administration
- Initial dosage for adults with seizure disorders not to exceed 1.5 mg/day
- Initial dosage for adults with panic disorder is 0.25 mg given in two divided doses
- Dosage adjustment for pediatric patients based on body weight
- Injection dosage for infants, children, and adults
Interaction
- No apparent alteration of phenytoin, carbamazepine or phenobarbital pharmacokinetics
- Effect on metabolism of other drugs not investigated
Contraindications
- Hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Contraindicated in acute narrow angle glaucoma
Side Effects
- CNS depression, drowsiness, ataxia, behavior problems, abnormal eye movements, aphonia, coma, tremor, vertigo, confusion, depression, amnesia, hallucinations, increased libido, insomnia, psychosis, palpitations
Pregnancy & Lactation
- Potential for producing congenital malformations
- Evidence of anticonvulsant drugs acting as teratogens
- Administration only if benefits outweigh risks
- Possibility of drug passing into maternal milk
Precautions & Warnings
- May increase incidence or precipitate generalized tonic-clonic seizures
- Concomitant use with valproic acid may produce absence status
Use in Special Populations
- Increased bronchial secretion in infants
- Greater pharmacologic effects in elderly patients
- Minimal impact of renal impairment on pharmacokinetics
- Potential impact of hepatic impairment on protein binding
Overdose Effects
- Symptoms of benzodiazepine overdose
- Seldom life-threatening when taken alone
- Treatment involves monitoring vital signs and supportive measures
- Use of flumazenil under monitored conditions
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Requirements for slow intravenous injection, intravenous infusion, and intramuscular injection
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
- Chemical Structure Image: URL
Common Questions about Disogen 0.5 mg Tablet
- Information on use as a sleeping pill
- Advisability of longer-term use
- Withdrawal symptoms upon discontinuation
- Monitoring for suicidal thoughts and actions
- Potential impact on weight and memory
- Harmfulness of excessive doses
- Contraindications for concurrent use with specific medications
- Quick Tips for safe usage