Disogen 2 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Biogen pharmaceuticals ltd |
| Also available as |
Title
Disogen 2mg Tablet
Categories
- Medicine
- Pharmaceutical
- Anti-epileptic
- Benzodiazepine
Description
Disogen 2mg Tablet is indicated for the treatment of panic disorder, with or without agoraphobia, and as an adjunct in the treatment of the Lennox-Gastaut Syndrome (petit mal variant), akinetic and myoclonic seizures. It has anticonvulsant, sedative, muscle relaxing, and anxiolytic effects. Adult dosage for seizures should not exceed 1.5 mg/day divided into three doses, while the initial dose for adults with panic disorder is 0.25 mg given in two divided doses. Pediatric patients should be given between 0.01 and 0.03 mg/kg/day but not to exceed 0.05 mg/kg/day. Disogen is contraindicated in patients with a history of hypersensitivity to benzodiazepines and in acute narrow angle glaucoma. Its most frequent side effects include CNS depression. During pregnancy, it may be administered if there is a compelling indication, but should be discontinued during breastfeeding.
Attributes
- Indications:
- Treatment of panic disorder
- Adjunct in the treatment of Lennox-Gastaut Syndrome
- Treatment of seizures
- Treatment option for panic attacks
- Pharmacology:
- Anticonvulsive effects
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- Enhancement of GABAergic neurotransmission
- Effect on serotonin
- Dosage & Administration:
- Initial dose for adults with seizure disorders
- Increase in dosage increments
- Maintenance dosage adjustment
- Initial dose for adults with panic disorder
- Dose for pediatric patients
- Oral and injection administration guidelines
- Interaction:
- No alteration of phenytoin, carbamazepine, or phenobarbital pharmacokinetics
- Effect on the metabolism of other drugs not investigated
- Contraindications:
- Hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Acute narrow angle glaucoma
- Side Effects:
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Coma
- Tremor
- Vertigo
- Confusion
- Increased libido
- Insomnia
- Psychosis
- Palpitations
- Pregnancy & Lactation:
- Potential for producing congenital malformations
- Evidence of anticonvulsant drugs as teratogens
- Administration during pregnancy dependent on compelling indication
- Passage into maternal milk in small amounts
- Discontinuation of breastfeeding if compelling indication for use
- Precautions & Warnings:
- Increased incidence or precipitate onset of generalized tonic-clonic seizures
- Concomitant use with valproic acid may produce absence status
- Use in Special Populations:
- Increased production of saliva and bronchial secretion in infants and small children
- Greater pharmacologic effects in elderly patients
- No dose adjustment required in renal impairment
- Significantly different plasma protein binding in cirrhotic patients
- Overdose Effects:
- Drowsiness
- Ataxia
- Dysarthria
- Nystagmus
- Areflexia
- Apnoea
- Hypotension
- Cardiorespiratory depression
- Coma
- Increased frequency of seizures
- Effect of other central nervous system depressants
- Treatment guidelines
- Therapeutic Class:
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
- Reconstitution:
- Guidelines for slow intravenous injection
- Guidelines for intravenous infusion
- Guidelines for intramuscular injection
- Storage Conditions:
- Keep in a dry place
- Away from light and heat
- Keep out of the reach of children
- Chemical Structure:
- Molecular Formula: C15H10ClN3O3
- Chemical Structure Image
- Common Questions:
- Therapeutic use as a sleeping pill
- Duration and withdrawal symptoms
- Early symptoms of suicidal thoughts
- Effect on weight gain
- Effect on memory
- Harmful potential of overdose
- Interactions with zolpidem and quetiapine
- Quick tips for safe use