Seclogen 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 9.00 (5 x 10: ৳ 450.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Omeprazole
Company Biogen pharmaceuticals ltd
Also available as
Seclogen 20 mg capsule

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of the antisecretory effect occurs within one hour
  • Maximum effect occurs within two hours
  • Inhibition of secretion lasts up to 72 hours
  • Secretory activity returns gradually over 3 to 5 days after discontinuation

Dosage

  • Various dosages for different conditions and age groups
  • Oral and IV administration
  • Dosage regimens for different durations

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Instructions for reconstitution and administration

Interactions

  • Potential interactions with ketoconazole, diazepam, phenytoin, warfarin, clarithromycin, amoxicillin, metronidazole, piroxicam, diclofenac, naproxen, alcohol, and food

Contraindications

  • Known hypersensitivity to the medication
  • Exclusion of malignancy before treatment initiation if gastric ulcer is suspected

Side Effects

  • Mild and reversible adverse reactions
  • Skin rash, urticaria, pruritus, photosensitivity, bullous eruption, erythema multiforme, angioedema, alopecia
  • Diarrhea, headache, constipation, nausea, vomiting, flatulence, abdominal pain
  • Dry mouth, stomatitis, candidiasis
  • Paraesthesia, dizziness, light headedness, faint feeling, somnolence, insomnia, vertigo
  • Mental confusion, agitation, depression, hallucinations
  • Arthritic and myalgic symptoms
  • Blurred vision, taste disturbance, peripheral edema, increased sweating, gynaecomastia
  • Leucopenia, thrombocytopenia, agranulocytosis, pancytopenia, anaphylactic shock
  • Malaise, fever, bronchospasm, encephalopathy, hepatitis, interstitial nephritis, hepatic failure
  • Increases in liver enzymes

Pregnancy & Lactation

  • No adverse effects on pregnancy or on the health of the fetus/newborn child
  • Safe to use during pregnancy
  • Information on passage into breast milk and effects on the neonate

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and the medication
  • Increased risk for osteoporosis-related fractures with PPI therapy
  • Atrophic gastritis noted occasionally in gastric corpus biopsies from long-term treatment
  • Potential methotrexate toxicities with PPIs

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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