Vorixen 200 mg (Tablet)
Unit Price: ৳ 120.00 (1 x 10: ৳ 1,200.00)
Strip Price: ৳ 1,200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Biogen pharmaceuticals ltd |
Indications
- Treatment of invasive aspergillosis
- Treatment of candidemia and disseminated candidiasis
- Treatment of esophageal candidiasis
- Treatment of serious infections caused by specific fungal species
- Treatment for patients intolerant of or refractory to other therapy
Pharmacology
- Contains voriconazole as the active ingredient
- Inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-alpha sterol demethylase
- Results in depletion of ergosterol in fungal cell membrane
Dosage & Administration
- Oral administration with specific dosages based on body weight
- Loading dose regimen for different infections
- Maintenance dose regimen for different infections
- Injection dosage for invasive aspergillosis and candidemia in nonneutropenic patients
- Different dosage for Scedosporiosis and Fusariosis
Interaction
- Potential interaction with CYP3A4, CYP2C9 and CYP2C19 inhibitors and inducers
- Potential increase in concentrations and activity of specific drugs
- Increased maintenance dosage with co-administration of certain drugs
Contraindications
- Known hypersensitivity to voriconazole or any other components of the drug
- Specific drug co-administrations contraindicated due to risk of serious adverse reactions or loss of efficacy
Side Effects
- Common side effects include abdominal pain, anemia, blurred vision, headache, chest pain, nausea, and diarrhea
Pregnancy & Lactation
- Limited data available for use in pregnant women
- Should be used during pregnancy only if potential benefit justifies potential risk to the fetus
Precautions & Warnings
- Long-term exposure requires careful assessment of benefit-risk balance
- Reported association with squamous cell carcinoma of the skin with long-term treatment
Use in Special Populations
- Efficacy not established for children under 12 years of age
Overdose Effects
- No data available for overdose effects
Therapeutic Class
- Belongs to the therapeutic class of other antifungal preparations
Reconstitution
- Instructions for reconstitution of suspension
- Specific reconstitution process and storage instructions provided
Storage Conditions
- Store in specific temperature and protected from light
- Keep out of reach of children
- Additional storage instructions for Vorixen powder for suspension