D-Vine 2000 IU/ml (Oral Solution)

50 ml bottle: ৳ 150.00

Medicine Details

Indications

  • Vitamin D3 deficiency
  • Calcium and phosphate absorption
  • Rickets prevention
  • Osteomalacia prevention
  • Osteoporosis prevention
  • Pre-eclampsia prevention
  • Immunity boost

Pharmacology

  • Active form: Calcitriol
  • Vitamin D receptors binding
  • Absorption in small intestine
  • Metabolism to 25-hydroxy Vitamin D3
  • Kidney hydroxylation to Calcitriol
  • Tissue storage
  • Elimination via faeces and urine

Dosage & Administration

  • 40000 IU weekly for adults
  • 20000 IU for children
  • 1000-2000 IU daily for tablets
  • 400-2000 IU for syrup
  • 100000-200000 IU every 6 months for injection

Interaction

  • Magnesium containing Antacids
  • Digoxin
  • Thiazide Diuretics
  • Corticosteroids
  • Phenytoin
  • Phenobarbital
  • Orlistat
  • Mineral Oil
  • Cholestyramine
  • Cholistipol

Contraindications

  • Hypercalcaemia
  • Hypersensitivity to Vitamin D3
  • Vitamin D3 toxicity

Side Effects

  • Anorexia
  • Lassitude
  • Nausea & vomiting
  • Diarrhea
  • Constipation
  • Weight loss
  • Polyuria
  • Sweating
  • Headache
  • Thirst
  • Vertigo
  • Raised concentrations of calcium and phosphate in plasma and urine

Pregnancy & Lactation

  • Safe use up to 4000 IU
  • Excretion in breast milk
  • Recommended daily intake of 400 IU for pregnant women
  • Infant overdose caution

Precautions & Warnings

  • Plasma-calcium concentration monitoring
  • High doses monitoring
  • Renal impairment monitoring
  • Digoxin consultation
  • Thiazide Diuretics consultation
  • Liver or kidney disease consultation
  • Primary hyperthyroidism consultation
  • Lymphoma consultation
  • Tuberculosis consultation

Use in Special Populations

  • Efficacy in children under 12 years not established

Overdose Effects

  • Hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

Storage Conditions

  • Keep below 30°C
  • Protected from light & moisture
  • Keep out of the reach of children

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