GBpoietin 5000 IU (IV/SC Injection)

5000 IU pre-filled syringe: ৳ 2,990.19

Medicine Details

Category Details
Generic Erythropoietin alfa
Company Globe biotech limited
Also available as
Gbpoietin 2000 iu injection Gbpoietin 4000 iu injection Gbpoietin 10000 iu injection

Title

  • GBpoietin - Erythropoiesis-stimulating Agent

Categories

  • Medicine
  • Healthcare
  • Therapeutic Class: Drugs for Haemolytic Hypoplastic & Renal Anemia

Description

  • Recombinant human erythropoietin (EPO)
  • 165 amino acid sequence identical to human urinary EPO
  • Expressed in Chinese hamster ovary cells
  • Molecular weight: 30,400 daltons

Indications

  • Treatment of anemia due to Chronic Kidney Disease (CKD) in patients on dialysis and not on dialysis
  • Treatment of anemia due to Zidovudine in HIV-infected patients
  • Treatment of anemia due to the effects of concomitant myelosuppressive chemotherapy
  • Reduction of allogeneic RBC transfusions in patients undergoing elective, noncardiac, nonvascular surgery
  • Prevention of anemia of prematurity in infants with a birth weight of 750 to 1500 gm and gestational age of less than 34 weeks

Dosage

  • Evaluation of Iron Stores and Nutritional Factors
  • Monitoring hemoglobin levels
  • Dosing adjustments based on hemoglobin response
  • Specific dosing for CKD patients on dialysis and not on dialysis, Zidovudine-treated HIV-infected patients, and patients on cancer chemotherapy
  • Prevention of anemia of prematurity dosing guidelines

Administration

  • Preparation and administration guidelines
  • Protection from light
  • Visual inspection prior to administration
  • Discard unused portions

Interaction

  • Potentiated effect by simultaneous therapeutic administration of a haematinic agent such as ferrous sulphate when deficiency state exists

Contraindications

  • Uncontrolled hypertension
  • Serious allergic reactions to Erythropoietin alfa
  • Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin

Side Effects

  • Adverse reactions in treated patients
  • Specific side effects for patients with CKD, Zidovudine-treated HIV-infected Patients, Cancer Patients on Chemotherapy, Surgery Patients, and Premature infants

Pregnancy & Lactation

  • Use in pregnancy if potential benefit outweighs potential risk to the fetus
  • Not recommended for pregnant or lactating surgical patients participating in an autologous blood predonation program
  • Caution in nursing women

Overdose Effects

  • Therapeutic margin
  • Management of overdosage
  • Possible severe hypertension following overdose

Storage Conditions

  • Temperature storage range: 2°C to 8°C
  • Protection from light
  • Original package storage

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