GBpoietin 5000 IU (IV/SC Injection)
5000 IU pre-filled syringe: ৳ 2,990.19
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythropoietin alfa |
| Company | Globe biotech limited |
| Also available as |
Title
- GBpoietin - Erythropoiesis-stimulating Agent
Categories
- Medicine
- Healthcare
- Therapeutic Class: Drugs for Haemolytic Hypoplastic & Renal Anemia
Description
- Recombinant human erythropoietin (EPO)
- 165 amino acid sequence identical to human urinary EPO
- Expressed in Chinese hamster ovary cells
- Molecular weight: 30,400 daltons
Indications
- Treatment of anemia due to Chronic Kidney Disease (CKD) in patients on dialysis and not on dialysis
- Treatment of anemia due to Zidovudine in HIV-infected patients
- Treatment of anemia due to the effects of concomitant myelosuppressive chemotherapy
- Reduction of allogeneic RBC transfusions in patients undergoing elective, noncardiac, nonvascular surgery
- Prevention of anemia of prematurity in infants with a birth weight of 750 to 1500 gm and gestational age of less than 34 weeks
Dosage
- Evaluation of Iron Stores and Nutritional Factors
- Monitoring hemoglobin levels
- Dosing adjustments based on hemoglobin response
- Specific dosing for CKD patients on dialysis and not on dialysis, Zidovudine-treated HIV-infected patients, and patients on cancer chemotherapy
- Prevention of anemia of prematurity dosing guidelines
Administration
- Preparation and administration guidelines
- Protection from light
- Visual inspection prior to administration
- Discard unused portions
Interaction
- Potentiated effect by simultaneous therapeutic administration of a haematinic agent such as ferrous sulphate when deficiency state exists
Contraindications
- Uncontrolled hypertension
- Serious allergic reactions to Erythropoietin alfa
- Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin
Side Effects
- Adverse reactions in treated patients
- Specific side effects for patients with CKD, Zidovudine-treated HIV-infected Patients, Cancer Patients on Chemotherapy, Surgery Patients, and Premature infants
Pregnancy & Lactation
- Use in pregnancy if potential benefit outweighs potential risk to the fetus
- Not recommended for pregnant or lactating surgical patients participating in an autologous blood predonation program
- Caution in nursing women
Overdose Effects
- Therapeutic margin
- Management of overdosage
- Possible severe hypertension following overdose
Storage Conditions
- Temperature storage range: 2°C to 8°C
- Protection from light
- Original package storage