Jectofer 500 mg/10 ml (IV Injection or Infusion)
10 ml vial: ৳ 700.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ferric carboxymaltose |
| Company | Globe pharmaceuticals ltd |
Indications
- Treatment of iron deficiency anaemia in adults
- Intolerance to oral iron
- Non-dialysis dependent chronic kidney disease
Description
- Colloidal iron (III) hydroxide in complex with Carboxymaltose
- Carbohydrate polymer that releases iron
Dosage & Administration
- Stepwise approach for posology
- Individual iron need determination based on body weight and Hb level
- Calculation and administration of the iron dose(s)
- Post-iron repletion assessments
Interaction
- Formal drug interaction studies not performed
Contraindications
- Hypersensitivity to the active substance or any excipients
- Serious hypersensitivity to other parenteral iron products
- Anaemia not attributed to iron deficiency
- Evidence of iron overload or disturbances in the utilisation of iron
Side Effects
- Infrequent and generally mild
- Common side effects: nausea, headache, dizziness, hypertension, injection site reactions
- Uncommon side effects: hypersensitivity, dysgeusia, tachycardia, hypotension, flushing, dyspnoea, abdominal pain, constipation, diarrhea
- Rare side effects: anaphylactoid reactions, loss of consciousness, anxiety, phlebitis, syncope
Pregnancy & Lactation
- No adequate and well-controlled trials in pregnant women
- Careful benefit/risk evaluation required before use during pregnancy
- Animal data indicate potential influence on fetal skeletal development
- Unlikely risk to breast-fed child based on limited data
Precautions & Warnings
- Serious hypersensitivity reactions reported
- Hypersensitivity monitoring during and after administration
- Transient elevations in systolic blood pressure
- Laboratory test alterations following administration
Use in Special Populations
- Limitations in doses for patients with haemodialysis-dependent chronic kidney disease
- Not recommended in children under 14 years
Overdose Effects
- Potential accumulation of iron in storage sites
- Monitoring of iron parameters recommended
- Consideration of iron chelator in cases of iron accumulation
Therapeutic Class
- Parenteral Iron Preparations
Storage Conditions
- Store in a cool (below 30°C) & dry place
- Avoid freezing
- Keep out of the reach of children