AirFlow 4 mg (Chewable Tablet)

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Montelukast sodium
Company Ad din pharmaceuticals ltd
Also available as
Airflow 10 mg tablet Airflow 5 mg chewable tablet

Title

  • AirFlow 4 mg Chewable Tablet

Categories

  • Medicine
  • Healthcare
  • Pharmaceutical

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Montelukast is a selective and orally active leukotriene receptor antagonist
  • Inhibits the cysteinyl leukotriene receptor (CysLT1)
  • Correlated with the pathophysiology of asthma & allergic rhinitis
  • Contributes to the signs and symptoms of asthma

Dosage & Administration

  • Montelukast 10 mg tablet once daily for adults and adolescents 15 years of age and older
  • Montelukast 5 mg tablet once daily for pediatric patients 6 to 14 years of age
  • Montelukast 4 mg tablet once daily for pediatric patients 2 to 5 years of age
  • Montelukast 4 mg oral granules once daily for pediatric patients 6 months to 5 years of age
  • No dosage adjustment is required in patients with mild-to-moderate hepatic insufficiency
  • No dosage adjustment is recommended in patients with renal insufficiency
  • The pharmacokinetic profile and the oral bioavailability of a single 10-mg oral dose of montelukast are similar in elderly and younger adults
  • No dosage adjustment in the elderly is required

Interaction

  • No apparent increase in adverse reactions when administered with other therapies routinely used in the prophylaxis and chronic treatment of asthma
  • Did not have clinically important effects on the pharmacokinetics of various drugs including theophylline, prednisone, prednisolone, oral contraceptives, terfenadine, digoxin, and warfarin
  • Used concomitantly with a wide range of commonly prescribed drugs in clinical studies without evidence of clinical adverse interactions
  • Phenobarbital, which induces hepatic metabolism, decreased the AUC of AirFlow approximately 40% following a single 10mg dose

Contraindications

  • Hypersensitivity to any component of this product

Side Effects

  • Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
  • Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor

Pregnancy & Lactation

  • Montelukast crosses the placenta following oral dosing in rats and rabbits
  • Caution should be exercised when given to a nursing mother

Precautions & Warnings

  • Not indicated for use in the reversal of bronchospasm in acute asthma attacks
  • Appropriate rescue medication should be available
  • Can be continued during acute exacerbations of asthma
  • Should not be abruptly substituted for inhaled or oral corticosteroids
  • Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
  • Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents

Overdose Effects

  • No adverse experiences in the majority of overdosage reports
  • The most frequently occurring adverse experiences were consistent with the safety profile of AirFlow
  • Usual supportive measures should be employed in the event of overdose

Therapeutic Class

  • Leukotriene receptor antagonists

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S
  • Chemical Structure: Montelukast Sodium

Common Questions

  • What is AirFlow 4 mg Chew. Tablet?
  • What is AirFlow 4 mg Chew. Tablet used for?
  • How soon can the effect of AirFlow 4 mg Chew. Tablet be observed?
  • How long does the effect of AirFlow 4 mg Chew. Tablet last?
  • Should I use AirFlow 4 mg Chew. Tablet empty stomach?
  • What if I miss a dose of AirFlow 4 mg Chew. Tablet?
  • Are there any pregnancy warnings for AirFlow 4 mg Chew. Tablet?
  • General Instructions

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