HCG 2500 IU/vial (IM/SC Injection)

Indications

• Ovulation induction in infertility due to anovulation or impaired follicle-ripening
• Preparation of follicles for puncture in controlled ovarian hyperstimulation programs (ART)
• Luteal phase support
• Threatened and habitual abortion
• Hypogonadotropic hypogonadism
• Delayed puberty associated with insufficient gonadotropic pituitary function
• Cryptorchidism
• Oligospermia

Pharmacology

• Pharmacodynamic Properties: Highly Purified Human Chorionic Gonadotrophin has LH activity
• Pharmacokinetic Properties: Maximal Human Chorionic Gonadotrophin plasma levels will be reached approximately six hours after a single injection

Dosage & Administration

• Female - Ovulation induction and preparation of follicles for puncture: 5000-10000IU Human Menopausal Gonadotrophin
• Female - Luteal phase support: 2500-5000IU
• Female - Threatened & habitual abortion: 5000IU twice weekly
• Male - Hypogonadotropic hypogonadism: 2500-5000 IU twice per week

Interaction

No interactions of clinical relevance are known

Contraindications

Known or suspected androgen-dependent tumours, such as prostatic carcinoma or breast carcinoma in the male

Side Effects

• Allergic reactions
• Unwanted ovarian hyperstimulation syndrome
• Water and sodium retention in males

Pregnancy & Lactation

• Pregnancy Category: X
• Lactation: Not to be used during lactation

Precautions & Warnings

Increased risk of multiple births, unwanted ovarian hyperstimulation

Use in Special Populations

• Pediatric Use: Induction of androgen secretion by HCG may induce precocious puberty
• Geriatric Use: Clinical studies did not include subjects aged 65 and over

Overdose Effects

Acute toxicity of urinary gonadotropin preparations is very low

Therapeutic Class

Female Sex hormones

Storage Conditions

• Store at 2°C-8°C (in refrigerator). Do not freeze
• Store below 25°C for a single period of not more than 3 months
• Protect from light & keep in dry place

Related Brands