Denixil Rapid 0.25 mg (Dispersible Tablet)
Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Renata limited |
| Also available as |
Indications
- Treatment of panic disorder
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome (petit mal variant)
- Treatment of akinetic seizures
- Treatment of myoclonic seizures
- Treatment of absence seizures (petit mal)
- Adjunct in the treatment of the Lennox-Gastaut Syndrome
- Adjunct in the treatment of akinetic seizures
- Adjunct in the treatment of myoclonic seizures
Pharmacology
- Exhibits anticonvulsive properties
- Exhibits sedative effects
- Exhibits muscle relaxing effects
- Exhibits anxiolytic effects
- Enhancement of GABAergic neurotransmission
- Positive allosteric modulation of GABA receptor
- Effect on serotonin
- Suppression of paroxysmal activity
Dosage & Administration
- Initial dose for adults with seizure disorders
- Initial dose for adults with panic disorder
- Initial dose for pediatric patients
- Dosage increment guidelines for seizure disorders
- Target dose for most patients with panic disorder
- Dosage adjustments based on response
- Maximum recommended daily dose
Interaction
- Effect on the pharmacokinetics of phenytoin
- Effect on the pharmacokinetics of carbamazepine
- Effect on the pharmacokinetics of phenobarbital
Contraindications
- History of hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Aphonia
- Coma
- Tremor
- Vertigo
- Confusion
- Depression
- Amnesia
- Hallucinations
- Hysteria
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential for producing congenital malformations
- Evidence of teratogenic effects of anticonvulsant drugs
- Consideration of potential benefits vs. risk to the fetus
- Administration during pregnancy
- Effects on the newborn
- Passage into maternal milk
- Discontinuation of breastfeeding
Precautions & Warnings
- Use in patients with multiple seizure disorders
- Possible increase in generalized tonic-clonic seizures
- Concomitant use of valproic acid
- Effects in pediatric patients
- Effects in geriatric patients
- Effects in patients with renal impairment
- Effects in patients with hepatic impairment
Use in Special Populations
- Saliva and bronchial secretion production in infants and small children
- Greater pharmacologic effects in elderly patients
- Effect on renal impairment
- Effect on hepatic impairment
Overdose Effects
- Symptoms of overdose
- Drowsiness
- Ataxia
- Dysarthria
- Nystagmus
- Areflexia
- Apnoea
- Hypotension
- Cardiorespiratory depression
- Coma
- Increased frequency of seizures
- Benzodiazepine respiratory depressant effects
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Preparation for slow intravenous injection
- Preparation for intravenous infusion
- Preparation for intramuscular injection
Storage Conditions
- Dry place
- Away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula
- C15H10ClN3O3
- Chemical Structure Image
Common Questions about Denixil Rapid 0.25 mg Tablet
- Use as a sleeping pill
- Long-term use
- Withdrawal symptoms
- Early symptoms of suicidal thoughts and actions
- Effect on weight
- Effect on memory
- Harmful effects of overdose
- Combination with other medications
- Quick tips for usage