Doxicap 50 mg (Capsule)
Medicine Details
Category | Details |
---|---|
Generic | Doxycycline hydrochloride |
Company | Renata limited |
Also available as |
Product Title
- Doxicap Tetracycline Antibiotic
Categories
- Medicine
- Antibiotic
Description
Doxicap is a highly active broad-spectrum antibiotic of tetracycline group. It is effective against a wide range of Gram-positive and Gram-negative bacteria, spirochete, mycoplasma, rickettsia and mycobacteria. Doxicap is used as an alternate to penicillin in the treatment of gonorrhoea and syphilis. Doxicap has its main mechanism of action on protein synthesis. Inside the bacterial cell, it inhibits protein synthesis.
Indications
- Respiratory tract infections
- Gastrointestinal tract infections
- Chlamydial infections
- Sexually transmitted diseases
- Other infections
Usual Dosage
- 200 mg on first day, then 100 mg daily for 7-10 days
- Severe infections: 200 mg daily for 10 days
- Acne: 100 mg daily
- Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days
Administration
Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing.
Interaction
Absorption of tetracyclines is impaired by antacid containing aluminium, calcium or magnesium, and iron containing preparation. Barbiturates, carbamazepine and phenytoin decrease half-life of doxycycline. Concurrent use of tetracyclines may render oral contraceptive less effective. Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosages. It is advisable to avoid giving tetracyclines in conjunction with penicillin.
Contraindications
- Hypersensitivity to tetracyclines
- Children under 8 years of age
- Pregnant women
- Lactating mothers
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Skin rashes
- Hemolytic anaemia
- Eosinophilia
Pregnancy & Lactation
Doxycycline should be avoided in pregnant women, and mothers taking these drugs should not breastfeed their child.
Precautions & Warnings
The use of drugs of the tetracycline class during tooth development may cause permanent discoloration of teeth and should not be used in children under 8 years.
Therapeutic Class
- Tetracycline group of drugs
Storage Conditions
- Store in a cool and dry place
- Protected from light