Diloren 1% w/w (Gel)

20 gm tube: ৳ 40.00

Medicine Details

Indications

  • Inflammatory and degenerative forms of rheumatism
  • Chronic involutive polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Sprain
  • Bruises
  • Dislocations
  • Episiotomy
  • Adnexitis
  • Chronic involutive polyarthritis
  • Acute gout
  • Peri-articular rheumatic disorders
  • Pain prevention for patients operated in the urogenital tract
  • Renal colic pain prevention

Pharmacology

Potent non-steroidal anti-inflammatory drug (NSAID) with pronounced anti-rheumatic, analgesic and antipyretic properties

Dosage & Administration

  • Diclofenac FC Tablet: 75-150 mg daily in 2 to 3 divided doses, preferably after food
  • Diclofenac SR Tablet: 1 tablet daily for adults, 1-3 mg/kg body wt. daily in divided doses for children
  • Diclofenac Dispersible Tablet: 2-3 tablets for adults, 1-3 mg/kg body weight for children
  • Diclofenac TR Capsule: One capsule daily
  • Diclofenac Suppository: 50 mg suppository 2-3 times daily for adults
  • Diclofenac injection: 1 ampoule daily for adults
  • Diclofenac Gel: 2-4 g applied to the skin 3-4 times daily

Interaction

  • Increased plasma concentrations of lithium and digoxin
  • Increased risk of haemorrhage with anticoagulant therapy
  • Can be given together with oral antidiabetic agents without influencing their clinical effect
  • Nephrotoxicity with concomitant use of cyclosporin and diclofenac
  • Serious toxicity when methotrexate and NSAIDs are given within 24 hours of each other
  • Convulsions may occur due to an interaction between quinolones and NSAIDs
  • Increased frequency of unwanted effects with co-administration of diclofenac with other systemic NSAIDs and steroids

Contraindications

Hypersensitivity to any ingredient, peptic ulcer, hypersensitivity to Diclofenac like other non-steroid anti-inflammatory agents

Side Effects

Mild, rare and transient adverse effects including epigastric pain, eructation, nausea, diarrhea, dizziness, headache, peripheral edema, skin reactions such as rash and eczema, local irritation and reddening of the skin

Pregnancy & Lactation

Should be employed only for compelling reasons during pregnancy, not recommended during the first trimester, a very insignificant quantity may be detected in breast milk

Precautions & Warnings

Close observation for peptic ulceration or gastrointestinal bleeding in rare instances, avoid contact with eyes or mucus membranes, not to be taken by mouth

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Store in a cool and dry place, protected from light, below 30°C, keep out of the reach of children

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