Lizox 400 mg (Tablet)

Unit Price: ৳ 60.00 (1 x 10: ৳ 600.00)
Strip Price: ৳ 600.00

Medicine Details

Category Details
Generic Linezolid
Company Aristopharma ltd
Also available as
Lizox 600 mg tablet

Indications

  • Nosocomial pneumonia
  • Community-acquired pneumonia
  • Complicated skin and skin structure infection
  • Uncomplicated skin and skin structure infections
  • Vancomycin-resistant Enterococcus faecium infections

Pharmacology

  • Synthetic antibacterial agent
  • Oxazolidinones class
  • In vitro activity against Gram positive aerobic bacteria
  • Bacterial protein synthesis inhibition
  • Bacteriostatic against enterococci and staphylococci

Dosage & Administration

  • Infection:
    • Nosocomial pneumonia
    • Community-acquired pneumonia
    • Complicated skin and skin structure infections
    • Uncomplicated skin and skin structure infections
  • Dosage, route and frequency of administration:
    • Pediatric patients
    • Adults and adolescent
    • Recommended duration of treatment (consecutive days)
    • Intravenous administration
    • Hepatic impairment
    • Use in children and adolescents

Interaction

  • Drug interaction with medication:
    • Reversible, nonselective inhibitor of monoamine oxidase
    • Potential for interaction with adrenergic and serotonergic agents
  • Drug interaction with food and others:
    • Avoid large quantities of tyramine-containing foods or beverages

Contraindications

  • Known hypersensitivity to Linezolid or any of the other product components
  • Concurrent use with monoamine oxidase inhibitors
  • Uncontrolled hypertension, pheochromocytoma, thyrotoxicosis

Side Effects

  • Diarrhea
  • Headache
  • Nausea
  • Oral and vaginal moniliasis
  • Hypertension
  • Dyspepsia
  • Pruritus
  • Tongue discoloration

Pregnancy & Lactation

  • Assessment of potential benefit versus potential risk
  • Presence in breast milk
  • Consideration of developmental and health benefits of breastfeeding

Precautions & Warnings

  • Weekly monitoring of complete blood counts
  • Ophthalmic evaluation in case of visual impairment symptoms
  • Not approved for catheter-related infections
  • Clostridium difficile-associated Diarrhea (CDAD) monitoring
  • Monitoring for potential increases in blood pressure
  • Recurrent nausea or vomiting evaluation
  • Hypoglycemia management

Overdose Effects

  • No reported cases
  • Symptomatic and supportive care
  • Approximately 30% removal during haemodialysis

Therapeutic Class

  • Macrolides

Reconstitution

  • Oral Suspension reconstitution process
  • Shake well before use
  • Storage guidelines

Storage Conditions

  • Room temperature storage
  • Protection from light and moisture
  • Keep away from children

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