Lizox 600 mg (Tablet)

Unit Price: ৳ 85.00 (1 x 10: ৳ 850.00)
Strip Price: ৳ 850.00

Medicine Details

Category Details
Generic Linezolid
Company Aristopharma ltd
Also available as
Lizox 400 mg tablet

Product title

  • Lizox

Categories

  • Antibacterial agent
  • Medication
  • Medicine
  • Antibiotic

Description

  • Lizox is indicated for the treatment of nosocomial pneumonia, community-acquired pneumonia, complicated skin and skin structure infection, uncomplicated skin and skin structure infections, vancomycin-resistant Enterococcus faecium infections.

Indications

  • Nosocomial pneumonia
  • Community-acquired pneumonia
  • Complicated skin and skin structure infection including diabetic foot infections
  • Uncomplicated skin and skin structure infections
  • Vancomycin-resistant Enterococcus faecium infections

Pharmacology

  • Selective inhibition of bacterial protein synthesis
  • Bacteriostatic against enterococci and staphylococci
  • Bactericidal for the majority of streptococci strains

Dosage administration

  • Dosage varies by type of infection
  • Oral route with or without food
  • Intravenous infusion over 30 to 120 minutes
  • No dose adjustment necessary when switching from intravenous to oral administration

Interaction medication

  • Reversible, nonselective inhibitor of monoamine oxidase
  • Potential interaction with adrenergic and serotonergic agents

Interaction food

  • Patients advised to avoid large quantities of foods or beverages with high tyramine content while taking Lizox

Contraindications

  • Known hypersensitivity to Linezolid or any other product components
  • Contraindicated in patients taking MAO inhibitors
  • Contraindicated in patients with uncontrolled hypertension, pheochromocytoma, thyrotoxicosis, carcinoid syndrome
  • Contraindicated in patients taking sympathomimetic agents, vasopressive agents, dopaminergic agents, serotonin re-uptake inhibitors, tricyclic antidepressants, serotonin 5-HT1 receptor agonists, meperidine, or buspirone

Side effects

  • Most adverse events reported were mild to moderate
  • Common adverse events include diarrhea, headache, and nausea
  • Other adverse events include oral and vaginal moniliasis, hypertension, dyspepsia, and localized abdominal pain

Pregnancy lactation

  • Available data on use in pregnant women
  • Linezolid present in breast milk
  • Benefits of breastfeeding should be considered

Precautions warnings

  • Complete blood counts should be monitored weekly
  • Ophthalmic evaluation recommended if visual impairment symptoms occur
  • Not approved for catheter-related infections
  • Monitor for potential increases in blood pressure
  • Immediate medical evaluation for certain symptoms

Overdose effects

  • No reported cases of overdose
  • Symptomatic and supportive care advised
  • Approximately 30% removed during 3 hours of hemodialysis

Therapeutic class

  • Macrolides

Reconstitution oral suspension

  • Shake the bottle to loosen powder
  • Add 75 ml of boiled and cooled water to the dry mixture
  • Shake the suspension well before each use
  • Store reconstituted suspension in a cool and dry place

Reconstitution intravenous administration

  • Lizox IV Injection supplied in single-use, ready-to-use infusion bottles
  • Administered by intravenous infusion over a period of 30 to 120 minutes
  • Do not use infusion vials in series connections

Storage conditions

  • Store at room temperature (15°C-30°C)
  • Away from light and moisture
  • Keep away from children

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