Renvista 50 mg (Tablet)
Unit Price: ৳ 350.00 (1 x 3: ৳ 1,050.00)
Strip Price: ৳ 1,050.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Roxadustat |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Treatment of symptomatic anemia in adult CKD patients
Description
- First-in-class HIF-PH inhibitor
- Promotes erythropoiesis
- Increases endogenous erythropoietin production
- Improves iron regulation
- Overcomes EPO-suppressive effects of inflammation
- Downregulates hepcidin
Pharmacology
- Orally bioavailable
- HIF-PH inhibitor
- Promotes HIF activity
- Increases endogenous erythropoietin production
- Reduces hepcidin expression
- Improves iron availability
- Boosts hemoglobin levels
- Regulates genes for erythropoiesis and iron metabolism
Dosage & Administration
- Oral administration
- Taken three times per week
- Individualized dose
- Dose adjustments based on patient condition
- Dose range: 20mg to 400mg
Interaction
- Potential drug-drug interactions
- Specific interactions with phosphate binders, gemfibrozil, probenecid, and statins
- Recommendations for dose adjustments
Side Effects
- Hypertension
- Vascular access thrombosis
- Diarrhea
- Peripheral edema
- Hyperkalemia
- Nausea
Pregnancy & Lactation
- Contraindicated in pregnant and breastfeeding women
Precautions & Warnings
- Caution in patients with pre-existing risk factors for thrombotic vascular events
- Caution in patients with a history of seizures
- Avoid in case of serious signs of infection or liver disorder
Use in Special Populations
- Not indicated in children
- Not recommended for use in patients with severe hepatic impairment
Overdose Effects
- Increased heart rate
- Potential increase in hemoglobin concentration
- Recommendations for dose reduction or interruption
Therapeutic Class
- Drugs for Haemolytic Hypoplastic & Renal Anemia
Storage Conditions
- Store below 30°C
- Keep away from light and moisture
- Keep out of the reach of children