Emparol-L 25 mg+5 mg (Tablet)

Unit Price: ৳ 40.00 (1 x 14: ৳ 560.00)
Strip Price: ৳ 560.00

Medicine Details

Indications

  • Adjunct to diet and exercise for type 2 diabetes mellitus

Pharmacology

  • Inhibition of DPP-4 enzyme
  • Inhibition of Sodium-glucose co-transporter 2 (SGLT2)

Dosage & Administration

  • Recommended daily dose of 10mg Empagliflozin and 5mg Linagliptin
  • Increased dose possible to 25mg Empagliflozin and 5mg Linagliptin

Renal impaired patients

  • Assessment of renal function before initiating
  • Discontinue if eGFR falls below 45 ml/min/1.73 m^2

Interactions

  • Increased urine volume and frequency with diuretics
  • Risk of hypoglycemia with insulin coadministration
  • Potential reduction in efficacy with P-glycoprotein or CYP3A4 inducers

Contraindications

  • Severe renal impairment
  • Hypersensitivity reaction to Linagliptin or Empagliflozin

Side Effects

  • Pancreatitis
  • Ketoacidosis
  • Volume Depletion
  • Genital Mycotic Infections
  • Hypersensitivity Reactions
  • Heart Failure

Pregnancy & Lactation

  • Not recommended in second and third trimesters
  • Limited data on use in pregnant women

Precautions & Warnings

  • Pancreatitis risk
  • Ketoacidosis risk
  • Hypotension and volume depletion
  • Urinary tract infection risk
  • Hypoglycemia risk
  • Genital mycotic infection risk

Overdose Effects

  • Contact Poison Control Center in case of overdose
  • Employ usual supportive measures

Therapeutic Class

  • Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors

Storage Conditions

  • Store below 30°C
  • Keep away from light and wet place
  • Keep out of reach of children

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