Progency 10 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
Category | Details |
---|---|
Generic | Dydrogesterone |
Company | Healthcare pharmaceuticals ltd |
Therapeutic Class
- Female Sex hormones
Indications
- Treatment of threatened miscarriage
- Treatment of habitual miscarriage
- Treatment of dysmenorrhoea
- Treatment of endometriosis
- Treatment of secondary amenorrhoea
- Treatment of irregular cycles
- Treatment of dysfunctional uterine bleeding
- Treatment of infertility due to luteal insufficiency
- Luteal support as part of an Assisted Reproductive Technology (ART)
- To counteract the effects of unopposed oestrogen on the endometrium in hormone replacement therapy for women with disorders due to natural or surgical induced menopause with an intact uterus
Pharmacology
- Orally-active progestogen
- Produces complete secretory endometrium in an oestrogen-primed uterus
- Protection against increased risk for endometrium hyperplasia and carcinogenesis induced by oestrogens
- No oestrogenic, androgenic, thermogenic, anabolic, or corticoid activity
Dosage & Administration
- Take exactly as prescribed by the doctor
Dosage for Progesterone deficiencies
- Threatened miscarriage: 40 mg (four tablets) at once, then 10 mg (one tablet) every eight hours until symptoms remit
- Habitual miscarriage: 10 mg (one tablet) twice daily until the twentieth week of pregnancy
- Dysmenorrhoea: 10 mg (one tablet) twice daily from day 5 to day 25 of the menstrual cycle
- Endometriosis: 10 mg (one tablet) two or three times daily from day 5 to day 25 of the cycle or continuously
- Dysfunctional bleeding (to arrest bleeding): 10 mg (one tablet) twice daily for five to seven days
- Dysfunctional bleeding (to prevent bleeding): 10 mg (one tablet) twice daily from day 11 to day 25 of the cycle
- Amenorrhoea: An oestrogen once daily from day 1 to day 25 of the cycle, together with 10 mg Presentation twice daily from day 11 to day 25 of the cycle
- Irregular cycles: 10 mg (one tablet) twice daily from day 11 to day 25 of the cycle
- Infertility due to luteal insufficiency: 10 mg (one tablet) daily from day 14 to day 25 of the cycle. The treatment should be continued for at least 6 consecutive cycles. It is advisable to continue this treatment during the first month of any pregnancy using the doses stated with respect to habitual miscarriage
- Luteal support as part of an Assisted Reproductive Technology (ART) treatment: 10 mg three times daily (three tablets daily) starting at the day of oocyte retrieval and continuing for 10 weeks if pregnancy is confirmed
Dosage for Hormone Replacement Therapy
- In combination with continuous oestrogentherapy, take one tablet daily for 14 consecutive days of a 28 day cycle
- In combination with cyclical oestrogen therapy take one tablet daily during the last 12 to 14 days of oestrogen therapy
- If endometrial biopsies or ultrasound reveal inadequate Presentationational response, 20 mg Dydrogesterone should be prescribed
Contraindications
- Known hypersensitivity to the active substance or to any of the excipients
- Known or suspected progestogen dependent neoplasms (e.g. meningioma)
Side Effects
- Migraines/headache
- Nausea
- Menstrual disorders
- Breast pain/tenderness
Pregnancy & Lactation
- No harmful effect of Dydrogesterone use during pregnancy
- No data on excretion of Dydrogesterone in mother's milk
- Progestogens and the metabolites pass to mother's milk in small quantities
- Dydrogesterone should not be used during the lactation period
Precautions & Warnings
- Before initiating treatment for abnormal bleeding, clarify the etiology
- Breakthrough bleeding and spotting may occur during the first months of treatment
- Investigate the reason for breakthrough bleeding or spotting
- Monitor for severe headache, migraine, symptoms indicating cerebral ischemia, marked increase in blood pressure, occurrence of venous thromboembolism (VTE)
- In cases of habitual or threatened abortion, ascertain the viability of the foetus
- Carefully monitor patients with a history of depression
Overdose Effects
- Progency was well tolerated after oral dosing (maximum daily dose is 360 mg)
- No reports of ill effects from overdose
- If a large overdose is discovered within two or three hours, consider gastric lavage
Storage Conditions
- Store at below 30°C in a dry place protected from light
- Keep out of reach of children