Xelcard 10 mg (Tablet)
Unit Price: ৳ 6.50 (3 x 10: ৳ 195.00)
Strip Price: ৳ 65.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
Dosage & Administration
- Usual dose: 5 mg once daily for hypertension
- Max dose: 10 mg once daily for hypertension
- 5 to 10 mg for chronic stable or vasospastic angina
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction between Xelcard and Digoxin
- No interaction between Xelcard and Cimetidine
- No significant alteration of Warfarin's effect by Xelcard
- Food does not alter the absorption of Xelcard
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy only if benefit justifies risk
- Not known whether excreted in human milk
- Discontinue nursing while Xelcard is administered
Precautions & Warnings
- Hepatic impairment
- Pregnancy
- Breast feeding
Use in Special Populations
- Different doses for children with hypertension
- Effect on blood pressure in children under 6 is not known
- Equal tolerance in elderly as in younger patients
- Normal dosage recommended for renal impairment
- Caution in dosage for mild to moderate hepatic impairment
- Initiate at lowest dose for severe hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked systemic hypotension
- Shock with fatal outcome
- Active cardiovascular support necessary
- Elevation of extremities
- Monitoring of cardiac and respiratory function
- Attention to circulating fluid volume and urine output
- Use of vasoconstrictor and intravenous calcium gluconate
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in a cool & dry place
- Protected from light