Venterol 5 mg/5 ml (Oral Solution)
Medicine Details
| Category | Details |
|---|---|
| Generic | Bambuterol hydrochloride |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Bronchial asthma
- Chronic bronchitis
- Emphysema
- Other lung diseases where bronchospasm is a complicating factor
Pharmacology
Bambuterol is a long-acting β2 adrenergic receptor agonist used in the treatment of asthma. It predominantly stimulates β2 receptors, producing relaxation of bronchial smooth muscle, inhibition of spasmogens, inhibition of edema, and increased mucociliary clearance.
Dosage & Administration
- Children 2-5 years: 10 mg (10 ml syrup)
- Children 6-12 years: 10-20 mg (10-20 ml syrup)
- Adult: 10-20 mg (10-20 ml syrup)
Interaction
- Succinylcholin
- MAOIs
- β2-blockers
- Corticosteroids
- Diuretics
- Muscle relaxants
- Sympathomimetic xanthine derivatives
Contraindications
- Hepatic impairment
- Liver cirrhosis
- Severely impaired liver function
Side Effects
- Fatigue
- Nausea
- Palpitation
- Headache
- Dizziness
- Tremor
Pregnancy & Lactation
Caution is recommended during the first trimester of pregnancy. Caution is also recommended if administered to breastfeeding patients. Transient hypoglycemia has been reported in newborn pre-term infants after maternal β2 agonist treatment.
Precautions & Warnings
- Dose reduction for severely impaired renal function patients
- Dose reduction for patients with genetic deficiencies of plasma cholinesterase
- Dose reduction for patients with severe ischemic heart disease
Overdose Effects
No reported bambuterol overdosage in humans. Symptoms may include headache, anxiety, tremor, nausea, muscle cramps, palpitations, tachycardia, arrhythmias, hypokalemia, hyperglycemia, and lactacidosis.
Therapeutic Class
Short-acting selective & β2-adrenoceptor stimulants
Storage Conditions
Keep below 30°C, away from light & moisture, and out of reach of children