Renafor-B (160 mcg+4.5 mcg)/puff (Inhaler)

120 metered doses: ৳ 980.00

Medicine Details

Category Details
Generic Budesonide formoterol fumarate
Company Renata limited
Also available as
Renafor b 80 mcg inhaler Renafor b 100 mcg inhalation capsule Renafor b 200 mcg inhalation capsule Renafor b 400 mcg inhalation capsule

Indications

  • Treatment of Asthma
  • Maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD)

Dosage

  • Adults and adolescents (12 years and older): The recommended maintenance dose is 1 puff twice daily or 2 puffs once daily.
  • Children: The usual maintenance dose is 1 -2 puffs once or twice daily.

Pharmacology

  • Budesonide is an anti-inflammatory corticosteroid with potent glucocorticoid activity.
  • Formoterol Fumarate Dihydrate is a long-acting, selective β2 - adrenergic agonist with a rapid onset of action.

Mode of Action

  • Budesonide exhibits potent glucocorticoid activity and weak mineralocorticoid activity.
  • Formoterol Fumarate Dihydrate is a selective β2 - adrenergic agonist with a rapid onset of action.

Administration

  • Steps for using the Inhaler according to National Asthma Guidelines for Medical Practitioners.
  • Instructions for cleaning the Inhaler to maintain hygiene.

Interaction

  • Co-administration with strong cytochrome P450 3A4 inhibitors should be avoided.
  • Beta-blockers should be used with caution as they may block bronchodilatory effects.

Contraindications

  • Primary treatment of status asthmaticus or other acute episodes of asthma or COPD.
  • Hypersensitivity to any of the ingredients in this preparation.

Side Effects

  • Common adverse events of Formoterol Fumarate include tremor, palpitations, and headache.
  • Adverse events associated with Budesonide include hoarseness, candida infection, and throat irritation.

Pregnancy & Lactation

  • No clinical data on exposed pregnancies are available for this combination.
  • No adequate data from use of Formoterol in pregnant women.

Precautions & Warnings

  • Caution should be taken in patients with diabetes mellitus and severe cardiovascular disorders.
  • Paradoxical bronchospasm may occur, and if experienced, the medication should be discontinued immediately.

Use in Special Populations

  • It is recommended that the height of children receiving prolonged treatment with inhaled corticosteroids is regularly monitored.

Overdose Effects

  • Overdose of Formoterol may lead to effects such as tremor, headache, and palpitations.
  • Acute overdosage with Budesonide, even in excessive doses, is not expected to be a clinical problem.

Storage Conditions

  • Inhalation capsules must not be swallowed and should be stored at or below 25°C temperature.
  • Remove Inhalation capsule from the blister pack only immediately before use.

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