Utrogest 200 mg (Capsule)

Title

• Utrogest Softgel Capsule

Categories

• Medicine
• Pharmaceutical

Description

• Progesterone Micronized Softgel Capsule with various indications, pharmacology, dosage & administration, interactions, contraindications, side effects, precautions & warnings, therapeutic class, and storage conditions

Indications

• Maintenance of Pregnancy in cases of Threatened / Recurrent abortion
• Luteal support during IUI and ART procedures IVF-ET
• Luteal support in cases of proven luteal phase insufficiency
• Post-menopausal hormone replacement therapy (HRT)
• Prevention of endometrial hyperplasia
• Progesterone challenge test in secondary amenorrhoea
• Cycle control along with estrogen therapy
• Dysfunctional uterine bleeding (DUB)
• Premenstrual tension
• Endometriosis
• Oocyte donation program
• Benign mastopathy

Pharmacology

• Contains micronised progesterone
• Structurally and biologically identical to natural endogenous progesterone
• Increased bioavailability when administered after meals
• Metabolized to pregnanediols and pregnanolones in the liver
• Excretion in bile and urine
• High concentrations in endometrial and breast tissue

Dosage & Administration

• Oral or vaginal routes administration
• Flexible dosage regimen based on indication and patient requirements
• Various recommended doses for different indications

Interaction

• Inhibition of metabolism by Ketoconazole

Contraindications

• Hypersensitivity
• Hepatic dysfunction
• Undiagnosed vaginal bleeding
• Porphyria
• Cancers of uterus and genital organs
• Breast cancers
• History of stroke or blood clots

Side Effects

• Devoid of estrogenic, androgenic, and mineralocorticoid effects
• Mild somnolence
• CNS side effects like depression
• Breast tenderness
• Bloating
• Reduction of side effects with vaginal route administration

Precautions & Warnings

• Severe renal insufficiency
• Diabetes mellitus
• Seizures
• Migraine
• Headache
• Heart diseases
• Depression

Therapeutic Class

• Drugs for menopausal symptoms
• Hormone replacement therapy
• Female Sex hormones
• Oral Contraceptive preparations

Storage Conditions

• Keep below 30°C temperature
• Keep away from light and moisture
• Keep out of the reach of children

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