Annova 500 mg (Tablet (Delayed Release))
Unit Price: ৳ 16.00 (5 x 10: ৳ 800.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Relief of rheumatoid arthritis
- Relief of osteoarthritis
- Relief of ankylosing spondylitis
- Relief of juvenile arthritis
- Relief of tendonitis
- Relief of bursitis
- Relief of acute gout
- Management of primary dysmenorrhea & pain
Pharmacology
- Blocks COX-1 and COX-2 enzymes
- Decreased prostaglandin synthesis
- Mediates antipyretic, analgesic, and anti-inflammatory properties
- Linked to gastrointestinal upset and renal toxicities
Dosage & Administration
- Taken with water after meals
- Adult dosage for rheumatoid arthritis/osteoarthritis/ankylosing spondylitis
- Adult dosage for acute gout
- Adult dosage for dysmenorrhoea
- Children dosage for juvenile rheumatoid arthritis
- Naproxen Gel application
Interaction
- ACE inhibitors diminish antihypertensive effect
- Antacids & Sucralfate delay absorption
- Aspirin increases adverse effects
- Diuretics reduce natriuretic effect
- Methotrexate enhances toxicity
- Warfarin increases risk of GI bleeding
- Selective Serotonin Reuptake Inhibitors increase risk of GI bleeding
Contraindications
- Known hypersensitivity to Naproxen
- Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- Treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal: Heartburn, abdominal pain, nausea, diarrhea, dyspepsia
- Central Nervous System: Headache, vertigo, drowsiness
- Dermatological: Pruritus (itching), purpura
- Cardiovascular: Edema, palpitation
- Others: Visual disturbances, hearing disturbances
Pregnancy & Lactation
- Adverse effect on fetus
- Causes delay in parturition
- Associated with premature closure of ductus arteriosus
- Excreted in small amounts in breast milk
Precautions & Warnings
- Renal effects: renal papillary necrosis and abnormal renal pathology
- Reports of acute interstitial nephritis, hematuria, proteinuria
- Hepatic effects: reports of moderate to severe jaundice
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Keep below 30°C
- Protected from light & moisture
- Keep out of the reach of children