D-Set 20000 IU (Capsule)

Unit Price: ৳ 20.00 (1 x 10: ৳ 200.00)
Strip Price: ৳ 200.00

Medicine Details

Indications

  • Prevention of rickets
  • Prevention of osteomalacia
  • Prevention of osteoporosis
  • Boosting immunity
  • Prevention of pre-eclampsia during pregnancy
  • Promoting healthy bones and teeth

Pharmacology

  • Active form: Calcitriol
  • Absorption in small intestine
  • Metabolized to 25-hydroxy Vitamin D3 (Calcidiol)
  • Second hydroxylation to 1,25-dihydroxy Vitamin D3 (Calcitriol in the kidney)
  • Storage in tissues such as fat and muscle
  • Elimination via faeces and urine

Dosage & Administration

  • Capsule dosage for adults
  • Capsule dosage for children (12-18 years)
  • Film-coated tablet dosage
  • Oroflash or chewable tablets dosage
  • Syrup dosage for patients with risk of Cholecalciferol deficiency
  • Injection dosage for prevention
  • Injection dosage for Vitamin D deficiency

Interaction

  • Interference with absorption and metabolism by other drugs
  • Increased need due to Corticosteroids

Contraindications

  • Hypercalcaemia
  • Hypersensitivity
  • Evidence of Vitamin D3 toxicity

Side Effects

  • Anorexia
  • Lassitude
  • Nausea & vomiting
  • Diarrhea
  • Constipation
  • Weight loss
  • Polyuria
  • Sweating
  • Headache
  • Thirst
  • Vertigo
  • Raised concentrations of calcium and phosphate in plasma and urine

Pregnancy & Lactation

  • Safe use during pregnancy
  • Excretion in breast milk
  • Overdose in infants induced by nursing mothers not observed
  • Impact on breast-fed child when additional vitamin D3 given to the mother

Precautions & Warnings

  • Monitoring plasma-calcium concentration
  • Consultation before supplementing with Vitamin D3 for users of Digoxin and Thiazide Diuretics
  • Consultation for users with liver or kidney disease, primary hyperthyroidism, lymphoma, tuberculosis, and granulomatous disease

Use in Special Populations

  • Safety & efficacy in children under 12 years not established

Overdose Effects

  • Hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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