Zasper 40 mg/vial (IV Injection)

40 mg vial: ৳ 105.00

Medicine Details

Category Details
Generic Esomeprazole
Company Maks drug limited
Also available as
Zasper 20 mg capsule Zasper 40 mg capsule

Title

  • Zasper 40 mg/vial Injection

Categories

  • Medicine
  • Healthcare
  • Pharmacology

Description

  • Proton pump inhibitor for relieving GERD symptoms
  • Used for healing erosive esophagitis
  • Recommended for maintenance of healing of erosive esophagitis
  • Combination therapy for Helicobacter pylori eradication
  • Indicated for Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia and duodenal & gastric ulcers
  • Available in oral dosage form and IV Injection/infusion

DosageForm

  • Tablet
  • Capsule
  • Oral Suspension
  • IV Injection
  • IV Infusion

DosageInstructions

  • 20 mg or 40 mg Once Daily for 4-8 Weeks for Erosive Esophagitis healing
  • 20 mg Once Daily for Maintenance
  • 20 mg Once Daily for Symptomatic GERD
  • Triple therapy for Helicobacter Pylori eradication
  • 20-80 mg Once Daily for Zollinger-Ellison Syndrome
  • 20-40 mg Once Daily for Acid-related Dyspepsia
  • 20 mg Once Daily for Duodenal Ulcer healing
  • 20-40 mg Once Daily for Gastric Ulcer healing
  • Specific dosage for Pediatric and Adult Patients with GERD and Gastric or Duodenal Ulcers

AdministrationInstructions

  • Swallow whole tablet or capsule one hour before a meal
  • Preparation and consumption of Oral Suspension
  • Preparation, dilution, and administration of IV Injection and IV Infusion

Pharmacology

  • Proton pump inhibitor - Esomeprazole suppresses gastric acid secretion
  • Enteric-coated pellet formulation for controlled absorption
  • Metabolized in the liver by CYP enzyme system
  • Extensive protein binding and excretion in urine and feces

Interaction

  • Metabolism by CYP2C19 and CYP3A4
  • Potential interactions with drugs affected by gastric pH
  • No significant interactions with certain drugs like phenytoin and warfarin

Contraindications

  • Hypersensitivity to any of the formulation

SideEffects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

PregnancyAndLactation

  • No well-controlled studies in pregnant women
  • No known excretion in breast milk
  • Discontinuation of breastfeeding if essential

PrecautionsAndWarnings

  • Symptomatic response does not exclude the presence of gastric malignancy
  • Instructions for patients with difficulty swallowing capsules
  • Use of antacids while taking Zasper

SpecialPopulations

  • Safety and effectiveness not established in paediatric patients
  • No significant differences in elderly and younger individuals
  • No dosage adjustment for mild to moderate hepatic insufficiency
  • Expected unaltered pharmacokinetics in renal impairment

OverdoseEffects

  • Acute toxicity signs in rat models
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

StorageConditions

  • Store at a temperature not exceeding 30°C
  • Dry place, protect from light and moisture
  • Keep out of reach of children

ChemicalStructure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

CommonQuestions

  • Uses and side effects of Zasper 40 mg/vial Injection
  • Pregnancy and breastfeeding considerations
  • Onset of action and quick tips for Zasper usage

Related Brands