Doctil 500 mg (Tablet)
Unit Price: ৳ 50.00 (5 x 4: ৳ 1,000.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Maks drug limited |
| Also available as |
Indications
- Treatment of infections caused by sensitive bacteria
- Pharyngitis/tonsillitis caused by Streptococcus pyogenes
- Acute bacterial otitis media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase producing strains) or Streptococcus pyogenes
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non beta-lactamase producing strains)
- Lower respiratory tract infections including pneumonia caused by various bacteria
- Skin and skin-structure infections caused by Staphylococcus aureus (including beta-lactamase producing strains) or Streptococcus pyogenes
- Urinary tract infections caused by E.coli or Klebsiella pneumoniae
- Bone and Joint Infections caused by Staphylococcus aureus
- Gonorrhoea caused by penicillinase-producing and non-penicillinase producing strains of Neisseria gonorrhoeae
- Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
Pharmacology
- Broad-spectrum bactericidal activity
- Effective against β-lactamase producing strains
- Good stability to bacterial β-lactamase
- Active against many ampicillin-resistant and amoxycillin-resistant strains
Dosage
- Dosage varies based on age and type of infection
- Dosage ranges from 250 mg to 1000 mg
- Different dosage for adolescents, adults, and pediatric patients
- Oral and parenteral dosage options available
- Specific dosage recommendations for different infections like pneumonia, otitis media, gonorrhoea, etc.
Administration
- Freshly reconstituted solution recommended
- Solution potency maintained for at least 24 hours at room temperature or 48 hours at 5°C
Interaction
- No potentially hazardous interactions reported
Contraindications
- Contraindicated in patients with known allergy to Cephalosporins
Side Effects
- Adverse effects are infrequent
- Mild and transient effects reported
- Effects include rashes and gastrointestinal disturbances
- Prolonged use may result in the overgrowth of non-susceptible organisms like Candida
Pregnancy & Lactation
- US FDA pregnancy category: B
- Limited studies in pregnant women
- Excreted in human milk
- Caution advised during pregnancy and lactation
Precautions & Warnings
- Careful use with concurrent treatment with potent diuretics or history of colitis
- May be given safely to patients hypersensitive to penicillin with rare cross reactions reported
Therapeutic Class
- Belongs to the second generation Cephalosporins
Reconstitution
- Specific reconstitution instructions provided for intramuscular and intravenous injection
Storage Conditions
- Store in a cool, dry place below 30°C
- Away from light & moisture
- Keep out of the reach of children