Doctil 125 mg/5 ml (Powder for Suspension)

70 ml bottle: ৳ 235.00

Medicine Details

Category Details
Generic Cefuroxime axetil
Company Maks drug limited
Also available as
Doctil 250 mg tablet Doctil 500 mg tablet Doctil 750 mg injection

Indications

  • Treatment of infections caused by sensitive bacteria
  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
  • Lower respiratory tract infections including pneumoniae caused by Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella spp., Staphylococcus aureus, E. coli
  • Skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
  • Urinary tract infections caused by E.coli or Klebsiella pneumoniae
  • Bone and Joint Infections caused by Staphylococcus aureus
  • Gonorrhoea caused by Neisseria gonorrhoeae
  • Early Lyme Disease caused by Borrelia burgdorferi

Pharmacology

  • Broad-spectrum bactericidal activity
  • Good stability to bacterial β-lactamase
  • Active against ampicillin-resistant and amoxycillin-resistant strains

Dosage

  • Different dosages for adolescents and adults
  • Different dosages for paediatric patients
  • Different dosages for parenteral use

Administration

  • Use of freshly reconstituted solution recommended
  • Maintains potency for at least 24 hours at room temperature

Interaction

  • No potentially hazardous interactions reported

Contraindications

  • Contraindicated in patients with known allergy to Cephalosporins

Side Effects

  • Infrequent and generally mild and transient adverse effects
  • Rashes and gastrointestinal disturbances reported
  • Prolonged use may result in overgrowth of non susceptible organisms

Pregnancy & Lactation

  • US FDA pregnancy category B
  • No adequate and well-controlled studies in pregnant women
  • Excreted in human milk

Precautions & Warnings

  • Caution with concurrent treatment with potent diuretics
  • Care needed for patients with history of colitis
  • Cephalosporins may be given safely to patients hypersensitive to penicillin

Therapeutic Class

  • Belongs to second generation Cephalosporins

Reconstitution

  • Specific procedures for intramuscular and intravenous injections

Storage Conditions

  • Store below 30° C, away from light & moisture

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