Doctil 750 mg/vial (IM/IV Injection)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Maks drug limited |
| Also available as |
Title
- Doctil Tablet
- Cefuroxime Tablet
Categories
- Medicine
- Antibiotic
- Pharmaceutical
Description
- Effective antibacterial agent
- Broad-spectrum bactericidal activity
DosageForm
Tablet or Suspension
AgeGroup
- Adolescents and adults (13 years and older)
- Paediatric Patients (3 months to 12 years)
- Children (above 3 months of age)
- Neonate
DosageInstructions
- Adolescents and adults:
- Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
- Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
- Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
- Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
- Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
- Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
- Uncomplicated Gonorrhoea: 1000 mg Single dose
- Community acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
- MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
- Early Lyme disease: 500 mg b.i.d. for 20 days
- Paediatric Patients:
- Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
- Acute otitis media: 30 mg/kg/day b.i.d for 10 days
- Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
- Impetigo: 30 mg/kg/day b.i.d for 10 days
- Parenteral:
- Adult: 750 mg three times daily by IM or IV injection
- Children (above 3 months of age): 30 - 100 mg/kg/day given in 3 or 4 equally divided doses
- Neonate: 30 - 100 mg/kg/day given in 2 or 3 equally divided doses
Administration
Freshly reconstituted solution recommended
Stability
Maintains potency for at least 24 hours at room temperature or 48 hours at 5o C
Interactions
No potentially hazardous interactions reported
Contraindications
Known allergy to Cephalosporins
SideEffects
- Rashes
- Gastrointestinal disturbances
- Prolonged use may result in overgrowth of non susceptible organisms e.g. Candida
PregnancyCategory
Category B
PregnancyWarning
Use during pregnancy only if clearly needed; Caution advised during breastfeeding
Precautions
Given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis
DrugClass
Second generation Cephalosporins
Reconstitution
Specific instructions for intramuscular and intravenous injections
StorageConditions
Store in a cool, dry place (below 30o C), away from light & moisture; Keep out of the reach of children
Pharmacology
Well-characterized and effective antibacterial agent, broad-spectrum bactericidal activity against a wide range of common pathogens, good stability to bacterial β-lactamase