Doctil Plus 500 mg+125 mg (Tablet)

Title

• Doctil Plus 500 mg Tablet

Categories

• Medicine
• Antibiotics
• Infectious Disease

Description

• Doctil Plus is indicated for the treatment of infections caused by sensitive bacteria

Dosage

• 250 mg b.i.d. for 5-10 days for Pharyngitis/Tonsillitis in adults
• 500 mg b.i.d. for 10 days for Acute bacterial maxillary sinusitis in adults
• 250-500 mg b.i.d. for 10 days for Acute bacterial exacerbation of chronic bronchitis in adults

Pharmacology

• Cefuroxime inhibits bacterial cell wall synthesis by interfering with the transpeptidation process
• Clavulanic acid protects Cefuroxime from degradation by beta lactamase enzymes

Interaction

• Probenecid increases the area under the serum concentration versus time curve by 50% when administered with Cefuroxime-Clavulanic Acid

Contraindications

• Known allergy to cephalosporin
• Pseudomembranous Colitis

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Abdominal discomfort or pain
• Renal dysfunction (rare)
• Anaphylaxis (rare)
• Angioedema (rare)

Pregnancy & Lactation

• Avoid in the first trimester if possible
• Safe for use in later pregnancy to treat urinary and other infections
• Excreted into breast milk in small quantities

Precautions & Warnings

• Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics

Therapeutic Class

• Second generation Cephalosporins

Storage Conditions

• Store in a cool, dry place (below 30°C), away from light and moisture
• Keep out of the reach of children

Common Questions

• Doctil Plus 500 mg Tablet starts working within 2-3 hours after taking it
• Effect lasts for an average duration of 4-8 hours
• Interaction with alcohol is unknown

Usability Features

• Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat
• Take it with food to avoid an upset stomach
• Stop taking Doctil Plus 500 mg Tablet and inform your doctor immediately if you develop symptoms of allergic reaction

Technical Specifications

• 250 mg b.i.d.
• 500 mg b.i.d.
• 20 mg/kg/day b.i.d. for paediatric dosage

Indications

• Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
• Acute Bacterial Otitis Media caused by Streptococcus pneumoniae
• Lower respiratory tract infections including pneumoniae
• Uncomplicated skin and skin-structure infections
• Uncomplicated urinary tract infections
• Bone and Joint Infections

Mode of Action

• Cefuroxime is a bactericidal second generation cephalosporin antibiotic
• Active against a wide range of Gram-positive and Gram-negative susceptible organisms including many beta-lactamase producing strains

Dosage & Administration

• 250 mg b.i.d. for Pharyngitis/tonsillitis in adults
• 250 mg b.i.d. for Acute bacterial maxillary sinusitis in adults
• 250-500 mg b.i.d. for Acute bacterial exacerbation of chronic bronchitis in adults
• 20 mg/kg/day b.i.d for Pharyngitis/Tonsillitis in paediatric patients
• 30 mg/kg/day b.i.d for Acute otitis media in paediatric patients

FAQs

• What is Doctil Plus 500 mg Tablet used for?
• How long does it take for Doctil Plus 500 mg Tablet to take effect?
• How long do the effects of this medicine last?
• Is Doctil Plus 500 mg Tablet safe to consume alcohol while taking this medicine?
• Can this medicine be taken during pregnancy?
• Can Doctil Plus 500 mg Tablet be taken while breast-feeding?

Quick Tips

• You have been prescribed Doctil Plus 500 mg Tablet medicine to treat bacterial infections, even if they have developed resistance
• Do not use leftover medicine for treating any infection in the future. Always consult your doctor before taking any antibiotic

Related Brands

• Zinaclav 500 mg+125 mg (Tablet) - dbl-pharmaceuticals-ltd
• Zinaclav 250 mg+62.5 mg (Tablet) - dbl-pharmaceuticals-ltd
• Nucef CV 500 mg+125 mg (Tablet) - nuvista-pharma-ltd
• Nucef CV 250 mg+62.5 mg (Tablet) - nuvista-pharma-ltd
• Doctil Plus (125 mg+31.25 mg)/5 ml (Powder for Suspension) - maks-drug-limited