Makzit 200 mg/5 ml (Powder for Suspension)

30 ml bottle: ৳ 145.00

Medicine Details

Category Details
Generic Azithromycin dihydrate
Company Maks drug limited
Also available as

Indications

  • Lower respiratory tract infections
  • Upper respiratory tract infections
  • Otitis media
  • Skin and soft tissue infections
  • Pharyngitis/tonsillitis
  • Bronchitis
  • Pneumonia
  • Non-gonococcal urethritis
  • Cervicitis

Pharmacology

  • Oral administration
  • Absorption on empty stomach
  • High concentration in phagocytes
  • Active transport to site of infection
  • Release during active phagocytosis
  • High tissue concentration
  • Ion trapping
  • High lipid solubility
  • Biliary excretion
  • Microbial protein synthesis inhibition

Dosage

  • 500 mg oral dosage for adults
  • 250 mg oral dosage for children
  • Single dose administration
  • Injection for IV infusion

Administration

  • Reconstitution procedure for suspension
  • Administration with meal timing

Interaction

  • Antacid interaction
  • Carbamazepine interaction
  • Cyclosporin interaction
  • Digoxin interaction
  • Ergot derivatives interaction
  • Methylprednisolone interaction
  • Theophylline interaction
  • Warfarin interaction
  • Terfenadine interaction

Contraindications

  • Hypersensitivity to macrolide antibiotic
  • Co-administration with ergot derivatives
  • Hepatic diseases

Side Effects

  • Gastrointestinal side effects
  • Nausea
  • Abdominal discomfort
  • Vomiting
  • Flatulence
  • Diarrhoea
  • Allergic reactions
  • Rash
  • Photosensitivity
  • Elevations in liver transaminases
  • Cholestatic jaundice
  • Reductions in neutrophil counts
  • Hearing impairment

Pregnancy & Lactation

  • Pregnancy Category B
  • No evidence of harm to fetus
  • Caution in breastfeeding women

Precautions & Warnings

  • Risk of serious allergic reactions
  • Long observation and treatment for allergic reactions

Use in Special Populations

  • No dose adjustment for mild renal impairment
  • Caution in severe renal impairment
  • Avoid use in hepatic impairment
  • No effect on driving and machine operation

Overdose Effects

  • Symptoms of macrolide antibiotic overdose
  • Gastric lavage and supportive measures

Storage Conditions

  • Dry place away from light and heat
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C38H72N2O12
  • Chemical Structure Image: [Link to image]

Common Questions about Makzit 200 mg/5 ml Suspension

  • Action and uses of the syrup
  • Common Side Effects
  • Instructions for storage and disposal
  • Possibility of diarrhea
  • Safety at prescribed doses
  • Classification as an antibiotic
  • Consultation if symptoms persist
  • Quick Tips for usage

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