Mydlam 7.5 mg (Tablet)
Unit Price: ৳ 9.60 (3 x 10: ৳ 288.00)
Strip Price: ৳ 96.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Midazolam |
| Company | Albion laboratories limited |
Title
- Mydlam - Midazolam Product
Categories
- Medicines
- Healthcare
- Sleep Aid
Description
- Sleep-inducing agent characterized by a rapid onset and short duration of action
- Exerts anxiolytic, anticonvulsant and muscle-relaxant effects
Indications
- Short-term treatment of insomnia
- Sedation in premedication before surgical or diagnostic procedures
Mode of Action
- Mediated through the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Increases the activity of GABA producing a sedating effect, relaxing skeletal muscles, and inducing sleep, anesthesia, and amnesia
- Binds to the benzodiazepine site on GABA-A receptors
- Receptors identified in different body tissues including the heart and skeletal muscle, mainly present in the central nervous system.
Dosage & Administration
- Oral dosage for adults: 7.5-15 mg daily
- In premedication: 15 mg of Midazolam should be given 30-60 minutes before the procedure
- Intramuscular administration for adults: 0.07-0.1 mg/kg body weight
- Rectal administration in children for preoperative sedation
Interaction
- Can enhance the central sedative effect of neuroleptics, tranquillizers, antidepressants, sleep-inducing drugs, analgesics, anaesthetics, antipsychotics, anxiolytics, antiepileptic drugs, and sedative antihistamines
Contraindications
- Severe respiratory insufficiency
- Severe hepatic insufficiency
- Myasthenia gravis
- Sleep apnea syndrome
- Known hypersensitivity to benzodiazepines or any component of the product
Side Effects
- Drowsiness, confusion, fatigue, headache, muscle weakness
- Fluctuations in vital signs including respiratory depression, apnea, variations in blood pressure, and pulse rate
Pregnancy & Lactation
- Should be avoided during pregnancy unless there is no safer alternative
- Should not be administered to breastfeeding mothers
Precautions & Warnings
- IV administration should be very slow
Overdose Effects
- May lead to coma, areflexia, cardiorespiratory depression, and apnea
- Effects of overdosage can be controlled with benzodiazepine antagonist flumazenil
Therapeutic Class
- Benzodiazepine hypnotics
- Benzodiazepine sedatives
Storage Conditions
- Protect from light and moisture
- Store in cool and dry place
- Keep out of the reach of children