Relnac 1% w/w (Gel)
10 gm tube: ৳ 13.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Albion laboratories limited |
Indications
- Rheumatology
- Inflammatory forms of rheumatism
- Degenerative forms of rheumatism
- Chronic involutive polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Pre-operative medication for pain prevention
- Inflammation and swelling prevention post-operatively and post-traumatically
- Pain prevention and treatment
- Patients operated in the urogenital tract
- Renal and biliary colic
Pharmacology
- Potent non-steroidal anti-inflammatory drug
- Pronounced anti-rheumatic properties
- Pronounced anti-inflammatory properties
- Analgesic properties
- Antipyretic properties
- Uricosuric effect
- Inhibits prostaglandin biosynthesis
- Rapid and complete absorption from the gastro-intestinal tract
- 99.7% bound to plasma proteins
- Metabolized in the liver
- Undergoes first pass metabolism
Dosage & Administration
- Adult dosage: 75-150 mg daily
- Children dosage: 1-3 mg of diclofenac/kg body weight daily
- Dosage reduction in long term use
- Dosage preferably after food
- Maximum daily dosage: 150 mg
- Dosage taken whole with liquid
- Dosage preferably at meal times
- Supplementation with conventional tablets if necessary
- Dose reduction in elderly or debilitated patients
- Maximum daily dose for suppository: 150 mg
- External use only for gel
Interaction
- Increased plasma concentrations of lithium and digoxin
- Increased risk of haemorrhage with anticoagulant therapy
- Can be given together with oral antidiabetic agents
- Cases of nephrotoxicity with cyclosporin concomitantly
- Serious toxicity when co-administered with methotrexate
- Potential convulsions with quinolone antimicrobials
- Increased frequency of unwanted effects with other NSAIDs and steroids
- Lowered plasma levels with aspirin
Contraindications
- Hypersensitivity to any ingredient
- Peptic ulcer
- Hypersensitivity to Diclofenac
- Contra-indicated in asthmatic patients
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions
- Local irritation and reddening of the skin
Pregnancy & Lactation
- Use only for compelling reasons during pregnancy
- Lowest effective dose should be used during pregnancy
- Not recommended during the first trimester of pregnancy
- Not recommended during lactation
Precautions & Warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Close observation for elderly patients
- Avoid contact with eyes or mucus membranes for gel
- Proper hand washing after application
- Not for oral consumption
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children