Relnac Plus (75 mg+20 mg)/2 ml (IM Injection)

2 ml ampoule: ৳ 14.00 (2 x 5: ৳ 140.00)

Medicine Details

Category Details
Generic Diclofenac sodium lidocaine hydrochloride
Company Albion laboratories limited

Indications

  • Relief of pain and inflammation in various conditions
  • Treatment of arthritic conditions
  • Management of musculoskeletal disorders
  • Relief of pain resulting from trauma
  • Control of pain and inflammation in minor surgeries

Pharmacology

  • Potent nonsteroidal antiinflammatory drug (NSAID)
  • Marked analgesic and antipyretic properties
  • Uricosuric effects
  • Inhibition of prostaglandin synthesis
  • Local anaesthetic properties of Lidocaine
  • Impairment of nerve impulse generation and conduction by Lidocaine

Dosage & Administration

  • Recommended dosage for adults
  • Recommended dosage for renal colic
  • Dosage for children with juvenile chronic arthritis
  • Recommended dosage for elderly patients

Interaction

  • Interaction with Lithium and Digoxin
  • Potential interaction with anticoagulants
  • Co-administration with antidiabetic agents
  • Cases of nephrotoxicity with Cyclosporin
  • Potential toxicity when co-administered with Methotrexate
  • Possibility of convulsions when co-administered with quinolone antimicrobials
  • Increased frequency of unwanted effects when co-administered with other NSAIDs and steroids
  • Inhibition of diuretic activity
  • Monitoring of serum potassium levels in co-administration with diuretics

Contraindications

  • Hypersensitivity to Diclofenac
  • Active or suspected peptic ulcer or gastrointestinal bleeding
  • Precipitation of asthma, urticaria, or acute rhinitis by Aspirin or other NSAIDs
  • Hypersensitivity to local anaesthetics of the amide type
  • Adams-Stokes syndrome or severe degrees of heart block
  • Hypersensitivity to any excipients used in the formulation

Side Effects

  • Mild and transient side effects
  • Gastrointestinal discomfort, nausea, diarrhea, and bleeding
  • Occasional injection site disorders
  • Rare instances of abscesses and local necrosis
  • Adverse effects on the central nervous system (CNS) due to Lidocaine

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Lowest effective dosage should be used
  • Avoid use during the last trimester of pregnancy
  • Detection of small quantities in breast milk with no expected undesirable effects on the infant

Precautions & Warnings

  • Close observation for patients with severe hepatic, cardiac, or renal insufficiency
  • Monitoring of renal function for patients on NSAIDs
  • Monitoring of liver function for patients on long term treatment with NSAIDs

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Temperature not exceeding 30°C
  • Dry place
  • Protected from light

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