Niltuf 200 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tolfenamic acid |
| Company | Veritas pharmaceuticals ltd |
Title
- Niltuf 200 mg Tablet
Categories
- Pain Relief
- Fever Reducer
- NSAID
- Migraine Relief
- Analgesic
- Post-operative Pain Relief
- Rheumatoid Arthritis Medication
Dimensions
- Tablet Size: 200 mg
- Packaging: Blister Pack
Color Options
- None
Functions
- Relieves Migraine Headache
- Reduces Mild to Moderate Pain
- Inhibits Inflammatory Mediators
- Potent Cyclooxygenase Enzyme Inhibitor
- Analgesic
- Reduces Fever
- Used for Rheumatoid Arthritis
Materials
- Tolfenamic Acid
- Pharmaceutical Ingredients
Technical Specifications
- Absorption: Readily absorbed from GI tract
- Peak Plasma Concentration: 60-90 minutes
- Bioavailability: 85%
- Distribution: 99% plasma protein binding
- Plasma Half-life: 2 hours
- Metabolism: Liver
- Excretion: 90% in urine, undergoes enterohepatic circulation
Design Elements
- Blister Pack
- Chemical Structure Image
Usability Features
- Adult Dosage: 200 mg for acute migraine attacks, 100-200 mg for mild to moderate pain (tid)
- Dosage for Renal Impairment
- Food Intake with Tablets
- Pediatric Dosage Regimen Not Established
- Caution for Patients with Asthma, Bleeding Disorders, Cardiovascular Diseases, etc.
- Storage: Cool, dry place away from light
Indications
- Relief of Migraine Headache
- Analgesic for Post-operative Pain and Fever
Pharmacology
- Inhibitor of Cyclooxygenase Enzyme
- Inhibits Synthesis of Inflammatory Mediators - Thromboxane B2, Prostaglandin E2
- Direct Antagonistic Action on Prostaglandin Receptors
- Pharmacokinetic Properties: Absorption, Distribution, Metabolism, Excretion
Interaction
- Absorption Interaction with Metoclopramide, Magnesium Hydroxide, Aluminium Hydroxide
- Increased Risk with Anticoagulants, Other NSAIDs
- Decreased Antihypertensive Response with Loop Diuretics, etc.
- Increased Plasma Concentration of Lithium, Methotrexate, Cardiac Glycosides
- Increased Risk of Nephrotoxicity with ACE Inhibitors, Ciclosporin, Tacrolimus, Diuretics
Contraindications
- Active Gastrointestinal Bleeding
- Active Gastrointestinal Ulceration
- History of Gastrointestinal Bleeding related to NSAID therapy
- Severe Heart Failure
Side Effects
- Rare: Alveolitis, Hepatic Damage, Pancreatitis, Pulmonary Eosinophilia, Stevens-Johnson Syndrome, Angioedema, Blood Disorder, Depression
- Common: Diarrhea, Dizziness, Drowsiness, Dysuria, Gastrointestinal Bleeding, Nausea, Hearing Disturbances, Rash
- Overdose Symptoms: Headache, Nausea, Vomiting, GI Bleeding, Drowsiness, Dizziness, Convulsion
Pregnancy & Lactation
- Not Recommended During Pregnancy unless Essential
- Avoid During Third Trimester of Pregnancy
- NSAIDs in Breast Milk in Low Concentrations
Precautions & Warnings
- Caution for Asthma, Bleeding Disorders, Cardiovascular Diseases, Peptic Ulceration, Hypertension, Liver Infection, etc.
- Increase Water Intake or Dose Reduction to Reduce Dysuria
Overdose Effects
- Symptoms include Headache, Nausea, Vomiting, Epigastric Pain, GI Bleeding, Diarrhea, Excitation, Coma, Convulsions
Therapeutic Class
- Rheumatoid Arthritis Medication
- NSAIDs
- Migraine Relief Medication
Storage Conditions
- Cool and Dry Place, Away from Light, Keep Out of Reach of Children