Nucef CV 250 mg+62.5 mg (Tablet)
Medicine Details
Category | Details |
---|---|
Generic | Cefuroxime axetil clavulanic acid |
Company | Nuvista pharma ltd |
Also available as |
Product Title
Nucef CV 250 mg Tablet
Categories
- Medicine
- Antibiotic
- Cephalosporin
- Cephalosporin Antibiotic
- Infection Treatment
Description
Nucef CV 250 mg Tablet is indicated for the treatment of infections caused by sensitive bacteria. It is a bactericidal second generation cephalosporin antibiotic which is active against a wide range of Gram-positive and Gram-negative susceptible organisms including many beta-lactamase producing strains.
Dosage
- 250 mg b.i.d. for 5-10 days for adults
- 20 mg/kg/day b.i.d for 5-10 days for pediatric patients
Indications
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
- Lower respiratory tract infections including pneumoniae caused by various bacteria
- Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
- Uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae
- Bone and Joint Infections caused by Staphylococcus aureus
- Uncomplicated Gonorrhoea caused by Neisseria gonorrhoeae
- Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
- Septicemia caused by various bacteria
- Meningitis caused by various bacteria
Mode of Action
Cefuroxime inhibits bacterial cell wall synthesis by interfering with the transpeptidation process. Clavulanic acid provides protection of Cefuroxime from degradation by beta lactamase enzymes and inactivates them.
Interaction
Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%. Drugs that reduce gastric acidity may result in a lower bioavailability of Cefuroxime and tend to cancel the effect of postprandial absorption.
Contraindications
- Known allergy to cephalosporin
- Pseudomembranous Colitis
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal discomfort or pain
- Renal dysfunction (Rare)
- Anaphylaxis (Rare)
- Angioedema (Rare)
Pregnancy & Lactation
Avoid use in the first trimester if possible. Can be safely used in later pregnancy to treat urinary and other infections. Excreted into breast milk in small quantities.
Precautions & Warnings
Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics & who has a history of colitis.
Therapeutic Class
Second generation Cephalosporins
Storage Conditions
Store in a cool, dry place (below 30°C), away from light and moisture. Keep out of the reach of children.
FAQs
- What is Nucef CV 250 mg Tablet?: Cefuroxime is the cephalosporin antibiotic and Clavulanic acid is a beta-lactamase inhibitor. Nucef CV 250 mg Tablet is indicated for the treatment of infections caused by sensitive bacteria.
- What is Nucef CV 250 mg Tablet used for?: Nucef CV 250 mg Tablet is used to treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhoea, pneumonia, and typhoid fever.
- How long does it take for Nucef CV 250 mg Tablet to take effect?: Nucef CV 250 mg Tablet starts working within 2-3 hours after taking it.
- How long do the effects of this medicine last?: The effect of Nucef CV 250 mg Tablet lasts for an average duration of 4-8 hours.
- Is Nucef CV 250 mg Tablet safe to consume alcohol while taking this medicine?: Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is Nucef CV 250 mg Tablet a habit forming medicine?: No habit-forming tendencies were reported for Nucef CV 250 mg Tablet.
- Can this medicine be taken during pregnancy?: Nucef CV 250 mg Tablet is safe to use in pregnancy to treat bacterial infections, but it is recommended to use this medicine only after consulting your doctor.
- Can Nucef CV 250 mg Tablet be taken while breast-feeding?: Nucef CV 250 mg Tablet is safe to use during breastfeeding. It enters into breast milk at low levels.
- Quick Tips:
- You have been prescribed Nucef CV 250 mg Tablet medicine to treat bacterial infections, even if they have developed resistance.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
- Take it with food to avoid an upset stomach.
- Diarrhea may occur as a side effect. Taking probiotics may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
- Stop taking Nucef CV 250 mg Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue, or breathing difficulties while taking it.
- Do not use leftover medicine for treating any infection in the future. Always consult your doctor before taking any antibiotic.
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