Emetus 8 mg (Tablet)
Unit Price: ৳ 11.00 (3 x 14: ৳ 462.00)
Strip Price: ৳ 154.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Osl pharma limited |
| Also available as |
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Description
- Orally dissolving film
- Emetus base as active ingredient
- Selective blocking agent of serotonin 5-HT3 receptor type
- Empirical formula: C18H19N3O
- Molecular weight: 293.3
Pharmacology
- Potent, highly selective 5HT3 receptor-antagonist
- Precise mode of action not fully known
- Action in control of nausea and vomiting
Dosage
- Dosage for adults and pediatric patients
- Different dosages for administration based on scenario (chemotherapy, radiotherapy, postoperative)
Administration
- Instructions for administration of oral soluble film
- Step by step guide for taking the film
Interaction
- Metabolism by hepatic cytochrome P-450 drug-metabolizing enzymes
- Potential effect of inducers or inhibitors of these enzymes
Contraindications
- Hypersensitivity to the drug or any of its components
- Contraindicated in concomitant use of apomorphine
Side Effects
- Frequently reported adverse events
- Range of potential side effects (headache, constipation, diarrhea, rash, sensation of flushing or warmth, hiccups, liver enzyme abnormalities, anaphylaxis, bronchospasm, tachycardia, angina, hypokalemia, shortness of breath)
Pregnancy & Lactation
- Results of 2-year studies in rats and mice
- Lack of mutagenicity
- Reproduction studies in pregnant rats and rabbits
- Cautiousness in administration to nursing women
Precautions & Warnings
- Reported hypersensitivity reactions
- Non-stimulating effect on gastric or intestinal peristalsis
- Inadvisability in replacing nasogastric suction
- Risk of masking a progressive ileus and/or gastric distension
Use in Special Populations
- Dosage adjustment for patients with impaired renal function
- Dosage adjustment for patients with impaired hepatic function
- Limited dosage information for pediatric patients aged 4 and below
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Temperature and storage recommendations
- Protection from light and moisture