Preganaaf 50 mg (Capsule)

Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Pregabalin
Company Naafco pharma ltd
Also available as
Preganaaf 75 mg capsule

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues

Dosage

  • Maximum recommended dose of 100 mg three times a day
  • Dose increase based on efficacy and tolerability
  • Recommended dose of 75 to 150 mg two times a day for postherpetic neuralgia
  • Recommended dose of 300 to 450 mg/day for fibromyalgia
  • Recommended dose range of 150 to 600 mg/day for neuropathic pain associated with spinal cord injury

Administration

  • Oral route of administration
  • Can be taken with or without food
  • Preganaaf CR tablet should be administered after an evening meal
  • Should be swallowed whole and should not be split, crushed or chewed

Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

  • Contraindicated in patients with known hypersensitivity to Preganaaf or any of its components

Side Effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Thinking abnormal

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Potential risk to fetus
  • Small amounts detected in the milk of lactating women
  • Breastfeeding not recommended during treatment

Precautions & Warnings

  • Angioedema can occur and may be associated with life-threatening respiratory compromise
  • Hypersensitivity reactions
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression may occur with concomitant CNS depressants
  • May cause dizziness and somnolence
  • Increased seizure frequency or other adverse reactions may occur if rapidly discontinued
  • May cause peripheral edema
  • Caution should be exercised when coadministering with thiazolidinedione antidiabetic agents

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • Safety and effectiveness not established for use in infants below the age of 1 month

Overdose Effects

  • Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C)
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C8H17NO2
  • Chemical Structure Image: [Link to image]

Common Questions

  • What is Preganaaf 50 mg Capsule?
  • How long do I need to use Preganaaf 50 mg Capsule before I see improvement in my condition?
  • At what frequency do I need to use Preganaaf 50 mg Capsule?
  • Should I use Preganaaf 50 mg Capsule empty stomach, before food or after food?
  • Instructions for storage and disposal of Preganaaf 50 mg Capsule
  • Does Preganaaf 50 mg Capsule work in the same way for each disease?
  • How long do I need to take Preganaaf 50 mg Capsule?
  • Is it necessary to continue taking Preganaaf 50 mg Capsule even if I feel fine?
  • Can I take Diazepam and Preganaaf 50 mg Capsule together?
  • Can the use of Preganaaf 50 mg Capsule cause weight gain?
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