Nasonaaf 500 mg+20 mg (Tablet (Delayed Release))

Unit Price: ৳ 18.00 (3 x 10: ৳ 540.00)
Strip Price: ৳ 180.00

Medicine Details

Category Details
Generic Naproxen sodium esomeprazole magnesium
Company Naafco pharma ltd

Indications

  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Decrease the risk of developing gastric ulcers

Pharmacology

  • Immediate release Esomeprazole Magnesium layer
  • Enteric-coated Naproxen core
  • Prostaglandin synthesis inhibition
  • Proton pump inhibitor action

Dosage

  • Lowest effective dose
  • Tablet strength variations for different conditions
  • Dosage based on weight for adolescent patients

Administration

  • Take 30 minutes before meals
  • Do not split, chew, crush, or dissolve the tablet

Interaction

  • Reduced antihypertensive effect with concomitant NSAIDs
  • Increased bleeding risk with warfarin
  • Interference with absorption of certain drugs

Contraindications

  • Hypersensitivity to components
  • History of allergic-type reactions to NSAIDs
  • Use during peri-operative period in CABG surgery

Side Effects

  • Decreased incidence of gastrointestinal side effects
  • Reduced occurrence of gastric ulcers
  • NSAID-associated adverse events risk
  • Gastrointestinal, cardiovascular, renal effects

Pregnancy & Lactation

  • Caution during first and second trimester
  • Contradicted during third trimester
  • Unknown excretion in human milk

Precautions & Warnings

  • Avoid concomitant use with certain NSAIDs
  • Minimize undesirable effects with lowest effective dose
  • Increased frequency of adverse reactions in older people
  • Consideration for patients with GI complications or cardiovascular risk factors

Use in Special Populations

  • Adjustment of dosage for elderly patients
  • Not recommended for patients with moderate to severe or severe renal impairment
  • Close monitoring for patients with mild to moderate hepatic impairment

Overdose Effects

  • Symptoms of Naproxen and Esomeprazole overdose
  • Symptomatic and supportive care for overdose management

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

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