Cadrol 2.5 mg (Tablet)
Unit Price: ৳ 6.04 (3 x 10: ৳ 181.20)
Strip Price: ৳ 60.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Bisoprolol hemifumarate |
| Company | Ethical drugs limited |
| Also available as |
Title
- Cadrol 2.5 mg Tablet
Categories
- Anti adrenergic agent (Beta blockers)
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Description
- Medication for High blood pressure (hypertension)
- Chest pain (angina)
- Heart failure
Therapeutic class
- Beta blockers
Indications
- Hypertension
- Angina
- Moderate to severe heart failure
Mode of action
- Selective ß1 blocker
- Reduction of arterial hypertension
- Minimal impact on lipid metabolism
- High therapeutic reliability
- Almost complete absorption from the gastrointestinal tract
- Extensive distribution
- Metabolized via oxidative pathways
- Renal elimination of metabolites
- Primarily metabolized via CYPSA4
- Elimination half-life of 10-12 hours
Dosage and administration
- Adult: Starting dose of 5 mg once daily
- Children: Safety and effectiveness not established
- Renal or hepatic impairment: Initial daily dose should be 5 mg
- Geriatrics: Dose adjustment usually not necessary
Interaction
- Beta blocking agents: Not recommended for combination use
- Catecholamine depleting drugs: Close monitoring required
- Centrally active antihypertensive agents: Withdraw β-blocker several days before discontinuing clonidine
- Antiarrhythmic agents: Use with care when myocardial depressants or inhibitors of A-V conduction are used
- Calcium channel blockers: Combined use can lead to prolongation of S-A and A-V conduction
Contraindications
- Cardiogenic shock
- Overt heart failure
- Second or third degree A-V block
- Right ventricular failure secondary to pulmonary hypertension
- Sinus bradycardia
Side effects
- Fatigue
- Dizziness
- Headache
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Abdominal pain
- Cold or numb extremities
- Muscle weakness or cramps
- Breathing difficulties
- Bronchospasm
Pregnancy and lactation
- Pregnancy: Use only if potential benefit justifies potential risk to the fetus
- Lactation: Small amounts detected in the milk; Consider essential use and stop nursing
Precautions and warnings
- Caution in adjusting the dose in patients with renal or hepatic impairment
- Patients with history of severe anaphylactic reaction may be more reactive to allergens
Storage conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical structure
- Molecular formula: C18H31NO4
- Chemical structure image url: https://medex.com.bd/storage/res/g-res-135-bisoprolol-hemifumarate-chemical-structure-rpXCAgy2GIOFKWUs5Peu.svg
Commonly asked questions
- Usage: By mouth, with or without food, once daily
- Side effects:
- Dizziness
- Fatigue
- Headache
- Slow heart rate
- Difficulty breathing
- Cold hands and feet
- Safety concerns:
- Talk to doctor before taking if have health conditions like asthma, diabetes, heart problems, liver or kidney problems, low blood pressure, depression
- Storage and disposal instructions: Keep in a cool dry place and in the original packaging