Cadrol 5 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Bisoprolol hemifumarate |
| Company | Ethical drugs limited |
| Also available as |
Indications
- Hypertension
- Angina
- Moderate to severe heart failure
Pharmacology
- Selective ß1 blocker
- Reduces heart rate and cardiac output
- Decreases arterial hypertension
- Affects lipid metabolism
- Extremely low inter and intra-individual variability of plasma concentration profiles
- Metabolized via oxidative pathways
- Primarily metabolized via CYPSA4
- Renally eliminated
- Elimination half-life of 10-12 hours
Dosage & Administration
- Usual starting dose of 5 mg once daily
- Increased to 10 mg if 5 mg is inadequate
- Maximum dose of 20 mg once daily
- Titration interval of 2 weeks
- Instructions for patients with renal or hepatic impairment
- No adjustment usually necessary for elderly
Interaction
- Not recommended with other β-blocking agents
- Monitoring required when used with catecholamine-depleting drugs
- Care needed when used with centrally active antihypertensive agents
- Usage precautions with antiarrhythmic agents and calcium channel blockers
Contraindications
- Cardiogenic shock
- Overt heart failure
- Second or third degree A-V block
- Right ventricular failure secondary to pulmonary hypertension
- Sinus bradycardia
Side Effects
- Fatigue
- Dizziness
- Headache
- Disturbances of the gut such as nausea, vomiting, diarrhea, constipation or abdominal pain
- Cold or numb extremities
- Muscle weakness or cramps
- Breathing difficulties
- Bronchospasm in people with asthma or COPD
Pregnancy & Lactation
- Potential risk to the fetus
- Consideration if benefits justify the risk
- Limited studies in pregnant women
- Potential excretion in human milk
Precautions & Warnings
- Use caution in patients with impaired renal or hepatic function
- Increased reactivity to allergens in patients with a history of severe anaphylactic reaction
- Unresponsiveness to usual doses of epinephrine in certain patients
Therapeutic Class
- Anti adrenergic agent (Beta blockers)
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula : C18H31NO4
- Chemical Structure image available
Common Questions about Cadrol 5 mg Tablet
- Blocks the effects of adrenaline to lower blood pressure and prevent chest pain
- Used for high blood pressure, chest pain, and heart failure
- Recommended intake by mouth, once daily, with or without food