Tagus 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)

Strip Price: ৳ 70.00

Medicine Details

Category	Details
Generic	Rabeprazole sodium
Company	Healthcare pharmaceuticals ltd
Also available as	Tagus 10 mg tablet

Indications

Active duodenal ulcer
Active benign gastric ulcer
Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
Zollinger-Ellison Syndrome
In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease

Pharmacology

Rabeprazole suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell.

Dosage

Recommended oral doses for active duodenal ulcer and active benign gastric ulcer
Recommended oral dose for erosive or ulcerative gastro-esophageal reflux disease (GERD)
Recommended oral dose for GERD long-term management (GERD maintenance)
Recommended oral dose for treatment of moderate to very severe GERD
Recommended oral dose for Zollinger-Ellison Syndrome
Dosing recommendation for treatment of H. pylori in peptic ulcer disease

Administration

Rabeprazole tablets should be taken in the morning, before eating, swallowed whole, not chewed or crushed.

Interaction

Potential interaction with pH-dependent compounds
Co-administration effects with ketoconazole or itraconazole
No interaction observed with liquid antacids
Absorption-based interaction with atazanavir

Contraindications

Hypersensitivity to the active substance or excipients
Contraindicated in pregnancy and breastfeeding

Side Effects

Headache
Diarrhea
Abdominal pain
Vomiting
Constipation
Dry mouth
Increased or decreased appetite
Muscle pain
Drowsiness
Dizziness

Pregnancy & Lactation

US FDA pregnancy category 'C'
Animal studies show no evidence of impaired fertility or harm to the fetus
No adequate and well-controlled studies in pregnant women
Rabeprazole likely to be excreted in human milk

Precautions & Warnings

Symptomatic response does not exclude the presence of malignancy
Regular surveillance for long-term treatments
Possible increase in risk of hip, wrist, and spine fracture
Risk of cross-hypersensitivity reactions
Hepatic enzyme abnormalities observed
Caution advised in patients with severe hepatic dysfunction
Co-administration with atazanavir not recommended
Possible increase in risk of gastrointestinal infections
Severe hypomagnesaemia reported in patients on prolonged treatment
Potential reduction in vitamin B12 absorption
Association with subacute cutaneous lupus erythematosus (SCLE)
Interference with laboratory tests

Use in Special Populations

No dosage adjustment necessary for renal or hepatic impairment
Not recommended for use in children

Overdose Effects

Effects generally minimal and reversible without medical intervention
No specific antidote known
Extensively protein bound and not dialysable

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Keep below 30°C temperature, away from light & moisture, out of the reach of children

Chemical Structure

Molecular Formula: C18H21N3O3S
Chemical Structure Image URL

Common Questions about Tagus 20 mg Tablet

Used to treat duodenal ulcer, gastric ulcer, GERD, Zollinger-Ellison Syndrome, Helicobacter pylori eradication
Common side effects include diarrhea, constipation, nausea, vomiting, headache, dizziness, rash, dry mouth
Should be taken with food, not recommended for use during pregnancy or breastfeeding
Overdose symptoms such as drowsiness, confusion, seizures may occur
Length of treatment depends on the condition being treated