Sinoline (100 mg+1.1 mg+14 mg)/5 ml (Syrup)

Indications

• Relief of cough
• Relief of congestive symptoms
• Aiding restful sleep

Composition

• Guaifenesin BP 100 mg
• Levomenthol BP 1.1 mg
• Diphenhydramine Hydrochloride BP 14 mg

Pharmacology

• Guaifenesin reduces viscosity of sputum
• Levomenthol has local anesthetic properties
• Diphenhydramine Hydrochloride has antitussive and antihistaminic properties

Dosage & Administration

• Dosage for adults and children over 12 years
• Dosage: 2 teaspoonfuls syrup 4 times a day
• Max dosage: 8 teaspoonfuls syrup in 24 hours
• Efficacy and safety not established in pediatric patients and adolescents

Interaction

• May potentiate effects of alcohol and other CNS depressants
• May potentiate effects of anticholinergics
• May result in tachycardia, dry mouth, urinary retention, etc.

Contraindications

• Contraindicated in individuals with hypersensitivity to the product
• Should not be administered to patients receiving MAOIs

Side Effects

• Drowsiness
• Dizziness
• Nausea and vomiting
• Gastrointestinal disturbance
• Dry mouth, nose, and throat
• Difficulty in urination
• Blurred vision

Pregnancy & Lactation

• Care should be taken during pregnancy
• Not associated with adverse effects in human fetus or infant

Precautions & Warnings

• May cause drowsiness
• Should not be taken by individuals with narrow-angle glaucoma
• Should not be used for persistent or chronic cough without physician's direction

Overdose Effects

• Guaifenesin may cause renal calculi
• Treatment should be symptomatic and supportive

Therapeutic Class

• Combined cough expectorants

Storage Conditions

• Temperature not exceeding 30°C
• Store in a dry place
• Protect from light and moisture
• Keep out of the reach of children

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