Aristopin 0.01% (Ophthalmic Solution)
5 ml drop: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Atropine sulfate ophthalmic |
| Company | Aristopharma ltd |
Product Title and Categories
- Aristopin Eye Drops
- Ophthalmic Medication
- Myopia Treatment
- Cycloplegic Agent
- Mydriatic Agent
Dosage Form
Eye Drops
Available Strengths
- 1%
- 0.01%
Composition
- Atropine 1% Eye Drops:
- Atropine Sulphate BP: 10 mg/ml
- Preservative: Benzalkonium Chloride 0.01%
- Atropine 0.01% Eye Drops:
- Atropine Sulphate USP: 0.1 mg/ml
- Preservative: Sodium Perborate 0.01%
Indications and Uses
- Cycloplegic for Refraction
- Mydriatic for Desired Dilatation of the Iris
- Uveitis
- Myopia Progression in Children
Pharmacological Action
Suppresses the progression of myopia
Mode of Action
- Targeted Receptors:
- M1
- M3
- M4
- Cell Signaling Pathways Affected:
- MEK-ERK-MAPK
- Transglutaminases
- Effect on Scleral Fibroblasts and Retina:
- Remodeling or Strengthening
- Reduction in Axial Length and Vitreous Chamber Depth
Dosage and Administration
- 1% Eye Drops:
- For Uveitis: One drop three times daily
- For Refraction: One drop in the eyes twice daily for one or two days before examination and one hour before examination, with pressure maintenance over lacrimal sac
- 0.01% Eye Drops: One drop to each eye at night with continued long-term administration for maximum benefit
Interactions
- Anticholinergics
- Antiglaucoma Agents
- Potassium Citrate
- Potassium Supplements
- Carbachol
- Physostigmine
- Pilocarpine
- CNS Medication
Contraindications
- Angle Closure Glaucoma or Suspected Angle Closure Glaucoma
Side Effects
- Blurred Vision
- Local Irritation
- Follicular Conjunctivitis
- Vascular Congestion
- Photophobia
Pregnancy and Lactation
- Systemic Absorption into Breast Milk
- Possible Adverse Effects in Nursing Infants
Precautions and Warnings
- Avoid in Children <4 years
- Caution in Down's Syndrome, Spastic Paralysis, or Brain Damage Patients
- Regular Clinical Reviews for Long-term Treatment
Overdose Effects and Management
- Flush the eye with water
- Seek Emergency Medical Attention
- Symptoms of Overdose
Therapeutic Class
Mydriatic and Cycloplegic Agents
Storage Conditions
- Store below 30°C
- Dry Place
- Away from Light
- Keep out of Reach of Children
- Do not use after 1 month of first opening