Aristopin 0.01% (Ophthalmic Solution)

5 ml drop: ৳ 150.00

Medicine Details

Category Details
Generic Atropine sulfate ophthalmic
Company Aristopharma ltd

Product Title and Categories

  • Aristopin Eye Drops
  • Ophthalmic Medication
  • Myopia Treatment
  • Cycloplegic Agent
  • Mydriatic Agent

Dosage Form

Eye Drops

Available Strengths

  • 1%
  • 0.01%

Composition

  • Atropine 1% Eye Drops:
    • Atropine Sulphate BP: 10 mg/ml
    • Preservative: Benzalkonium Chloride 0.01%
  • Atropine 0.01% Eye Drops:
    • Atropine Sulphate USP: 0.1 mg/ml
    • Preservative: Sodium Perborate 0.01%

Indications and Uses

  • Cycloplegic for Refraction
  • Mydriatic for Desired Dilatation of the Iris
  • Uveitis
  • Myopia Progression in Children

Pharmacological Action

Suppresses the progression of myopia

Mode of Action

  • Targeted Receptors:
    • M1
    • M3
    • M4
  • Cell Signaling Pathways Affected:
    • MEK-ERK-MAPK
    • Transglutaminases
  • Effect on Scleral Fibroblasts and Retina:
    • Remodeling or Strengthening
    • Reduction in Axial Length and Vitreous Chamber Depth

Dosage and Administration

  • 1% Eye Drops:
    • For Uveitis: One drop three times daily
    • For Refraction: One drop in the eyes twice daily for one or two days before examination and one hour before examination, with pressure maintenance over lacrimal sac
  • 0.01% Eye Drops: One drop to each eye at night with continued long-term administration for maximum benefit

Interactions

  • Anticholinergics
  • Antiglaucoma Agents
  • Potassium Citrate
  • Potassium Supplements
  • Carbachol
  • Physostigmine
  • Pilocarpine
  • CNS Medication

Contraindications

  • Angle Closure Glaucoma or Suspected Angle Closure Glaucoma

Side Effects

  • Blurred Vision
  • Local Irritation
  • Follicular Conjunctivitis
  • Vascular Congestion
  • Photophobia

Pregnancy and Lactation

  • Systemic Absorption into Breast Milk
  • Possible Adverse Effects in Nursing Infants

Precautions and Warnings

  • Avoid in Children <4 years
  • Caution in Down's Syndrome, Spastic Paralysis, or Brain Damage Patients
  • Regular Clinical Reviews for Long-term Treatment

Overdose Effects and Management

  • Flush the eye with water
  • Seek Emergency Medical Attention
  • Symptoms of Overdose

Therapeutic Class

Mydriatic and Cycloplegic Agents

Storage Conditions

  • Store below 30°C
  • Dry Place
  • Away from Light
  • Keep out of Reach of Children
  • Do not use after 1 month of first opening

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