RenoAlfa 600 mg (Tablet)
Unit Price: ৳ 40.00 (3 x 10: ৳ 1,200.00)
Strip Price: ৳ 400.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amino acid ketoanalogues |
| Company | Everest pharmaceuticals ltd |
Title and Categories
- RenoAlfa Amino Acid Keto Analogues
- Nutritional Supplement
- Genito-Urinary Preparations
Indications
- Prevention & treatment of damages due to faulty or deficient protein metabolism in chronic kidney disease
- Limited dietary protein intake of 40 gm/day or less (adult)
- Patients with glomerular filtration rate (GFR) less than 25 ml/min
Composition
- Ingredients:
- Calcium-3-methyl-2-oxo-valerate (α-ketoanalogue of isoleucine, calcium-salt)
- Calcium-4-methyl-2-oxo-valerate (α-ketoanalogue of leucine, calcium-salt)
- Calcium-2-oxo-3-phenylpropionate (α-ketoanalogue of phenylalanine, calcium-salt)
- Calcium-3-methyl-2-oxobutyrate (α-ketoanalogue of valine, calcium salt)
- Calcium-DL-2-hydroxy-4-(methylthio) butyrate (α-hydroxyanalogue to methionine, calcium-salt)
- L-lysine acetate USP (eqv. to Lysine 75mg)
- L-threonine USP
- L-tryptophan USP
- L-histidine USP as Histidine Hydrochloride Monohydrate
- L-tyrosine USP
Pharmacology
- Contains essential amino acids and ketoanalogues
- Improves metabolism of protein in the body
- Enhances renal function
- Minimizes amino-nitrogen intake
Dosage & Administration
- Take 4-8 tablets 3 times a day during meals (adults with 70 kg body weight)
- Swallow whole, do not chew
- Food should contain 40 g/day protein or less (adults)
- Ingest during meals for proper absorption and metabolisation
- Administer as long as GFR is between 5 and about 25mL/minute
Interactions
- Concomitant administration of calcium-containing drugs may cause or aggravate elevated serum calcium levels
- Adjust dose if necessary with aluminum hydroxide administration
- Avoid taking with drugs that form hardly soluble compounds with calcium
- May increase susceptibility to cardioactive glycosides and risk for arrhythmia
- Monitor serum phosphate levels with concomitant administration of aluminum hydroxide
Contraindications
- Hypersensitivity to active substances or excipients
- Hypercalcemia
- Disturbed amino acid metabolism
Side Effects
- Hypercalcaemia (Very Rare)
- Reduce intake of vitamin D if hypercalcaemia occurs
- Consider reducing dose of RenoAlfa and other calcium sources if hypercalcaemia persists
Pregnancy & Lactation
- No adequate data in pregnant women
- Animal studies do not indicate harmful effects, exercise caution when prescribing to pregnant women
- No experience in lactation
Precautions & Warnings
- Regular monitoring of serum calcium level
- Ensure sufficient calorie intake
- Attention in presence of hereditary phenylketonuria as it contains phenylalanine
- Monitor serum phosphate levels with concomitant administration of aluminum hydroxide
Therapeutic Class
Other genito-urinary preparations
Storage Conditions
Store at a temperature not exceeding 30°C in a dry place. Protect from light & moisture