RenoAlfa 600 mg (Tablet)

Unit Price: ৳ 40.00 (3 x 10: ৳ 1,200.00)
Strip Price: ৳ 400.00

Medicine Details

Title and Categories

  • RenoAlfa Amino Acid Keto Analogues
  • Nutritional Supplement
  • Genito-Urinary Preparations

Indications

  • Prevention & treatment of damages due to faulty or deficient protein metabolism in chronic kidney disease
  • Limited dietary protein intake of 40 gm/day or less (adult)
  • Patients with glomerular filtration rate (GFR) less than 25 ml/min

Composition

  • Ingredients:
    • Calcium-3-methyl-2-oxo-valerate (α-ketoanalogue of isoleucine, calcium-salt)
    • Calcium-4-methyl-2-oxo-valerate (α-ketoanalogue of leucine, calcium-salt)
    • Calcium-2-oxo-3-phenylpropionate (α-ketoanalogue of phenylalanine, calcium-salt)
    • Calcium-3-methyl-2-oxobutyrate (α-ketoanalogue of valine, calcium salt)
    • Calcium-DL-2-hydroxy-4-(methylthio) butyrate (α-hydroxyanalogue to methionine, calcium-salt)
    • L-lysine acetate USP (eqv. to Lysine 75mg)
    • L-threonine USP
    • L-tryptophan USP
    • L-histidine USP as Histidine Hydrochloride Monohydrate
    • L-tyrosine USP

Pharmacology

  • Contains essential amino acids and ketoanalogues
  • Improves metabolism of protein in the body
  • Enhances renal function
  • Minimizes amino-nitrogen intake

Dosage & Administration

  • Take 4-8 tablets 3 times a day during meals (adults with 70 kg body weight)
  • Swallow whole, do not chew
  • Food should contain 40 g/day protein or less (adults)
  • Ingest during meals for proper absorption and metabolisation
  • Administer as long as GFR is between 5 and about 25mL/minute

Interactions

  • Concomitant administration of calcium-containing drugs may cause or aggravate elevated serum calcium levels
  • Adjust dose if necessary with aluminum hydroxide administration
  • Avoid taking with drugs that form hardly soluble compounds with calcium
  • May increase susceptibility to cardioactive glycosides and risk for arrhythmia
  • Monitor serum phosphate levels with concomitant administration of aluminum hydroxide

Contraindications

  • Hypersensitivity to active substances or excipients
  • Hypercalcemia
  • Disturbed amino acid metabolism

Side Effects

  • Hypercalcaemia (Very Rare)
  • Reduce intake of vitamin D if hypercalcaemia occurs
  • Consider reducing dose of RenoAlfa and other calcium sources if hypercalcaemia persists

Pregnancy & Lactation

  • No adequate data in pregnant women
  • Animal studies do not indicate harmful effects, exercise caution when prescribing to pregnant women
  • No experience in lactation

Precautions & Warnings

  • Regular monitoring of serum calcium level
  • Ensure sufficient calorie intake
  • Attention in presence of hereditary phenylketonuria as it contains phenylalanine
  • Monitor serum phosphate levels with concomitant administration of aluminum hydroxide

Therapeutic Class

Other genito-urinary preparations

Storage Conditions

Store at a temperature not exceeding 30°C in a dry place. Protect from light & moisture

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